95481-41-7Relevant academic research and scientific papers
SEQUENTIAL DIRECTED ORTHO METALATION REACTIONS. A SYNTHESIS OF ANTHRAMYCIN.
Reed, N. J.,Snieckus, V.
, p. 5505 - 5508 (1984)
The pyrrolobenzodiazepine 2 , a key intermediate in the synthesis of anthramycin (1), has been prepared via a new approach involving two sequential directed ortho metalation reactions (4) and a previously unreported isatoic anhydride construction (8(*) 9).
