SEQUENTIAL DIRECTED ORTHO METALATION REACTIONS. A SYNTHESIS OF ANTHRAMYCIN.

DOI: 10.1016/S0040-4039(01)81611-7

Source and publish data:

Tetrahedron Letters p. 5505 - 5508 (1984)

Update date:2022-08-04

Topics:

Authors:

Reed, N. J.

Snieckus, V.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(01)81611-7

The pyrrolo<1,4>benzodiazepine 2 , a key intermediate in the synthesis of anthramycin (1), has been prepared via a new approach involving two sequential directed ortho metalation reactions (4) and a previously unreported isatoic anhydride construction (8(*) 9).

Full text of DOI:10.1016/S0040-4039(01)81611-7

Products guided by the article

Product name:Carbamic acid, [2-(methoxymethoxy)-3-methylphenyl]-, 1,1-dimethylethyl ester

Cas No:95481-41-7

R&D Labs maybe for 95481-41-7

XI'AN CHUKANG BIOTECHNOLOGY CO.,LTD

Contact:29-63685658 63685359

Address:Room 3-1202,Building 1,Oriental oasis,East of Xianning Road,Xi'an,Shaanxi 710043 P.R.China
Shandong Bolode Bio-Technology Co., LTD

Contact:+86-0531-58966870

Address:136 Jingyi Road,Huaiyin District,Jinan,Shandong,China
Zhenjiang Haitong Chemical Industry Co., Ltd.

Contact:+86 (511) 8448-0369

Address:Baoyan Town, Dantu District, Zhenjiang City, Jiangsu, China
Jiaxing Trustworthy Import And Export Co.,Ltd

Contact:+86-573-82030555

Address:Room 1202, Unit B, Charming plaza,No.1558 East Zhongshan Road , Jiaxing City, Zhejiang Province, China.
Zhengzhou Minzhong Pharmaceutical Co.,ltd

Contact:0086-371-65797115

Address:15/F,Jiangshan Bldg, NO.126 Huanghe Road,Zhengzhou, China

Relevant to this article

Novel benzodifuran analogs as potent 5-HT_2A receptor agonists with ocular hypotensive activity

Doi:10.1016/j.bmcl.2007.03.073
(2007)
Discovery of oxazole and triazole derivatives as potent and selective S1P₁ agonists through pharmacophore-guided design

Doi:10.1016/j.ejmech.2014.07.081
(2014)
Studies towards the identification of a new generation of atypical antipsychotic agents

Doi:10.1016/j.bmcl.2006.10.036
(2007)
Oxygen-Transfer Reactions Catalyzed by Nitropalladium(II) Complexes. Reactivity of Bis(μ-chloro)bishept-2-yl-C,N>dipalladium: Cleavage of the C-Pd Bond

Doi:10.1021/jo00386a006
(1987)
N-ARYL-N-<1,2,5-TRIMETHYLPIPERIDYL-4-PROPAMIDES> AND THEIR ANALGESIC ACTIVITY

Doi:10.1007/BF00773819
(1984)
Acid - Base reactions of methylnickel hydroxo, alkoxo, and amide complexes with carbon acids. Studies on the reactivity of noncyclic nickel enolates

Doi:10.1021/om7007259
(2007)

Article Doi