955005-75-1

Basic information

• Product Name: 2,2-bis(hydroxymethyl)propyl (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)-phenoxy]-1-butenyl]cyclopentyl]-5-heptenoate
• Synonyms: 2,2-bis(hydroxymethyl)propyl (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)-phenoxy]-1-butenyl]cyclopentyl]-5-heptenoate
• CAS NO: 955005-75-1
• Molecular Weight: 560.608
• Mol File: 955005-75-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2,2-bis(hydroxymethyl)propyl (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)-phenoxy]-1-butenyl]cyclopentyl]-5-heptenoate(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-bis(hydroxymethyl)propyl (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)-phenoxy]-1-butenyl]cyclopentyl]-5-heptenoate(955005-75-1)
• EPA Substance Registry System: 2,2-bis(hydroxymethyl)propyl (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)-phenoxy]-1-butenyl]cyclopentyl]-5-heptenoate(955005-75-1)

Safety Data

• Hazardous Substances Data: 955005-75-1(Hazardous Substances Data)

Upstream product

• 98-17-9 3-Trifluoromethylphenol 
• 1420790-89-1 (S)-(+)-2-hydroxy-3-(3-trifluoromethylphenoxy)propyl pivalate 
• 1420790-92-6 (S)-(-)-2-(tert-butyldimethylsilyloxy)-3-(3-trifluoromethylphenoxy)propyl pivalate 
• 1420790-96-0 (R)-(-)-2-(tert-Butyldimethylsilyloxy)-3-(3-trifluoromethylphenoxy)propan-1-ol 
• 1420790-99-3 (S)-(-)-2-(tert-butyldimethylsilyloxy)-3-(3-trifluoromethylphenoxy)propanal 

Downstream Products

• 54276-17-4 (+)-fluprostenol 

Relevant articles and documents

PROCESS FOR PREPARATION OF PROSTAGLANDIN F2 ALPHA ANALOGUES

A convergent synthesis of the prostaglandin F2α analogues, travoprost and bimatoprost, was developed employing Julia-Lythgoe olefination of the structurally advanced phenylsulfone with an enantiomerically pure aldehyde ω-chain synthon. The novel convergent strategy allows the synthesis of a whole series of prostaglandin analogues of high purity from a common and structurally advanced prostaglandin intermediate.

PROCESS FOR PREPARATION OF PROSTAGLANDIN F2α ANALOGUES

A convergent synthesis of the prostaglandin F2α analogues, travoprost and bimatoprost, was developed employing Julia-Lythgoe olefination of the structurally advanced phenylsulfone with an enantiomerically pure aldehyde ω-chain synthon. The novel convergent strategy allows the synthesis of a whole series of prostaglandin analogues of high purity from a common and structurally advanced prostaglandin intermediate.