95514-58-2

Upstream product

• 15022-08-9 diallylcarbonate 
• 41865-47-8 2-<(2-tetrahydropyranyl)oxy>-2-phenylacetonitrile 
• 16308-66-0 allyl butyl carbonate 
• 70122-88-2 allyl isopropyl carbonate 
• 74562-19-9 N,N-Diisopropylcarbamidsaeure-(2-propenylester) 
• 70122-89-3 tert-butyl allyl carbonate 
• 35466-83-2 allyl methyl carbonate 

Downstream Products

• 43058-55-5 Allylphenylketoncyanhydrin 
• 495-41-0 1-phenylbut-2-en-1-one 

Relevant academic research and scientific papers

Allylic Carbonates. Efficient Allylating Agents of Carbonucleophiles in Palladium-Catalyzed Reactions under Neutral Conditions

Allylation of β-keto esters or malonates was carried out in good yields under neutral conditions by using allylic carbonates in the presence of palladium-phospine catalyst.Although simple ketones, esters, nitriles, and sulfones hardly react with allylic carbonates, α-alkenyl or α-aryl ketones, esters, nitriles, and sulfones were also allylated by using palladium-bis(diphenylphosphino)ethane catalyst under neutral conditions.

PALLADIUM-CATALYZED REACTION OF ALLYL CARBAMATES; ALLYLATION OF CARBONUCLEOPHILES, AND PROTECTION-DEPROTECTION OF AMINES

Allylation of carbonucleophiles with allylic carbamates under neutral conditions has been studied.The C-allylation of carbonucleophile is competitive with the N-allylation of amines, and the structure of amines is crucial for the selectivity.Bulky secondary amines gave the best results.Also a new method of protection-deprotection of amines as carbamates has been developed.Smooth deprotection is possible by the palladium-catalyzed reaction of allyl carbamates with formic acid.This method is particulary useful for primary amines, including optically active amino acids.