955940-39-3

Usage

Uses

Used in Medicinal Chemistry:
(2R,4S)-4-azido-2-phenyltetrahydro-2H-pyran is used as a building block for the development of new pharmaceuticals or drug candidates. Its unique molecular structure and potential biological activities make it a promising candidate for further research and development in this field.
Used in Organic Chemistry:
(2R,4S)-4-azido-2-phenyltetrahydro-2H-pyran is used as a starting material for the synthesis of other related compounds. Its molecular structure and properties make it a valuable component in the development of new organic compounds and materials.

Upstream product

• 627-27-0 homoalylic alcohol 
• 100-52-7 benzaldehyde 

Relevant academic research and scientific papers

A diastereoselective synthesis of 4-azidotetrahydropyrans via the Prins-cyclization

A three component coupling of aldehydes, homoallylic alcohols and sodium azide is achieved in the presence of trifluoroacetic acid in dichloromethane to produce 4-azidotetrahydropyran derivatives in high yields with all cis-selectivity. The use of trifluo

1,2,4-TRIAZOLO[4,3-a]PYRIDINE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS

The present invention relates to novel triazolo [4,3-a]pyridine derivatives of Formula (I), wherein all radicals are as defined in the claims. The compounds according to the invention are positive allosteric modulators of the metabotropic glutamate receptor subtype 2 ("mGluR2"), which are useful for the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which the mGluR2 subtype of metabotropic receptors is involved. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes to prepare such compounds and compositions, and to the use of such compounds for the prevention or treatment of neurological and psychiatric disorders and diseases in which mGluR2 is involved.

PURINE AND IMIDAZOPYRIDINE DERIVATIVES FOR IMMUNOSUPPRESSION

The present invention provides novel purine and imidazopyridine derivatives useful for the prevention and treatment of autoimmune diseases, inflammatory disease, mast cell mediated disease and transplant rejection. The compounds are of the general formulas ( I ) and ( II ).