95611-88-4

Usage

Uses

Used in Pharmaceutical Industry:
5-(4-CHLORO-2-NITRO-PHENYL)-FURAN-2-CARBOXYLIC ACID is used as a building block for the synthesis of various biologically active compounds and drug candidates due to its unique structural features and reactivity.
Used in Organic Chemistry Research:
In the field of organic chemistry, 5-(4-CHLORO-2-NITRO-PHENYL)-FURAN-2-CARBOXYLIC ACID is used as a valuable intermediate in the production of a variety of organic compounds, including heterocyclic and aromatic compounds, for its potential to contribute to the development of new chemical entities and reactions.
Used in Medicinal Chemistry and Drug Development:
5-(4-CHLORO-2-NITRO-PHENYL)-FURAN-2-CARBOXYLIC ACID is utilized for its potential applications in medicinal chemistry and drug development, given its structural features that may offer new avenues for the creation of therapeutic agents.

InChI:InChI=1/C11H6ClNO5/c12-6-1-2-7(8(5-6)13(16)17)9-3-4-10(18-9)11(14)15/h1-5H,(H,14,15)

Upstream product

• 480439-09-6 5-(4-chloro-2-nitrophenyl)-2-furaldehyde 
• 1899-24-7 5-bromo-2-furancarboxaldehyde 
• 88-14-2 2-furanoic acid 
• 89-63-4 4-Chloro-2-nitroaniline 

Downstream Products

• 1007551-99-6 C₁₆H₈Cl₂N₂O₅ 
• 1144110-84-8 C₂₁H₁₄ClN₅O₃S₂ 
• 1365714-66-4 4-methoxybenzyl 5-(4-chloro-2-nitrophenyl)-2-furoate 
• 1365714-46-0 3,4,5-trimethoxybenzyl 5-(4-chloro-2-nitrophenyl)-2-furoate 
• 1365714-72-2 3,4,5-trimethoxybenzyl 5-(4-chloro-2-nitrophenyl)-2-furamide 
• 95611-99-7 5-(2-Azido-4-chloro-phenyl)-furan-2-carboxylic acid ethyl ester 
• 95611-95-3 ethyl 5-(2-amino-4-chlorophenyl)-2-furancarboxylate 
• 95611-92-0 5-(4-Chloro-2-nitro-phenyl)-furan-2-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

Derivatives of (R)-3-(5-Furanyl)carboxamido-2-aminopropanoic Acid as Potent NMDA Receptor Glycine Site Agonists with GluN2 Subunit-Specific Activity

NMDA receptors mediate glutamatergic neurotransmission and are therapeutic targets due to their involvement in a variety of psychiatric and neurological disorders. Here, we describe the design and synthesis of a series of (R)-3-(5-furanyl)carboxamido-2-am

Synthesis and antimicrobial activities of some new triazolothiadiazoles bearing 4-methylthiobenzyl moiety

A series of substituted triazolothiadiazoles (6a-j and 7a-j) have been synthesized by condensing 4-amino-3-[4-methylthiobenzyl]-4H-1,2,4-triazole-5-thiol (5) with substituted aryl furoic acids/aromatic acids in the presence of POCl3. The triazole (5) was obtained by the fusion of 4-methylthiophenyl acetic acid (4) with thiocarbohydrazide. The structures of newly synthesized compounds are characterized by elemental analysis, IR, 1H NMR and mass spectroscopic studies and were screened for their antimicrobial activities. The preliminary results revealed that some of the compounds exhibited promising antimicrobial activities.

Synthesis of some thiadiazolotriazinone derivatives as possible antimicrobial agents

A series of 7-substituted-3-t-butyl 4(H)-1,3,4-thiadiazolo(2,3-c)-1,2,4- triazine-4-one (3) have been synthesized by condensing 4-amino-6-t-butyl-3- mercapto-1,2,4-triazin-5(4H)-one (1) with substituted Arylfuroic acids (2) using POCl3 as a cyclizing agen