95656-76-1 Usage
Ethanolamine class
Member
It belongs to a class of organic compounds that have an ethanolamine backbone.
Phenyl ring
Present
The compound features a phenyl ring, which is a six-membered carbon ring with alternating single and double bonds.
Chlorine substituent
3'-position
A chlorine atom is attached to the 3'-position of the phenyl ring, which can influence the compound's reactivity and properties.
Cyano substituent
5'-position
A cyano group (C≡N) is attached to the 5'-position of the phenyl ring, which can affect the compound's polarity and reactivity.
Amino group
4'-position
An amino group (-NH2) is attached to the 4'-position of the phenyl ring, which can participate in hydrogen bonding and other interactions.
Sec-butylamino group
Attached to ethanolamine backbone
A secondary butylamine (sec-butylamino) group is attached to the ethanolamine backbone, which can influence the compound's solubility and steric properties.
Potential applications
Medicinal chemistry
Specific properties and uses
Context-dependent
The specific properties and potential uses of 1-(4'-Amino-3'-chloro-5'-cyano-phenyl)-2-sec.butylamino-ethanol may vary depending on the context in which it is being studied or employed, such as in drug design or chemical synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 95656-76-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,5,6,5 and 6 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 95656-76:
(7*9)+(6*5)+(5*6)+(4*5)+(3*6)+(2*7)+(1*6)=181
181 % 10 = 1
So 95656-76-1 is a valid CAS Registry Number.
95656-76-1Relevant academic research and scientific papers
Synthesis of further amino-halogen-substituted phenyl-aminoethanols
Kruger,Keck,Noll,Pieper
, p. 1612 - 1624 (2007/10/02)
Starting from clenbuterol as a lead structure, new 4-amino-phenyl-aminoethanol analogues have been synthesized by different approaches. In these compounds one or both of the chlorine atoms of clenbuterol are replaced by other residues. This has led to compounds with high intrinsic β2-mimetic and/or β1-blocking activities. 1-(4-Amino-3-chloro-5-trifluoromethyl-phenyl)-2-tert.-butylamino-ethanol hydrochloride (mabuterol) has been selected for clinical development. A detailed description is also given of the syntheses of new intermediate acetophenone derivatives as well as of the resolution of mabuterol into its enantiomers.
BRONCHOSPASMOLYTIC 1-(P-AMINO-PHENYL)-2-AMINO-ETHANOLS-(1) AND SALTS
-
, (2008/06/13)
Racemic and optically active compounds of the formula wherein R1 is hydrogen, fluorine, chlorine, bromine, iodine or cyano, R2 is fluorine, trifluoromethyl, nitro or cyano, and R3 is alkyl of 3 to 5 carbon atoms, hydroxy(alkyl of 3 to 5 carbon atoms), cycloalkyl of 3 to 5 carbon atoms, 1-(3,4-methylenedioxy-phenyl)-2-propyl or 1-(p-hydroxy-phenyl)-2-propyl, and non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as their salts are useful as analgesics, uterospasmolytics, bronchospasmolytics and antispastics for the skeletal musculature, and especially as beta 2-receptor mimetics and beta 1-receptor blockers
