95675-71-1Relevant academic research and scientific papers
Proton and deuterium nuclear magnetic resonance studies on iron(II) complexes of N-substituted porphyrins
Balch, Alan L.,Chan, Yee-Wai,La Mar, Gerd N.,Latos-Grazynski, Lechoslaw,Renner, Mark W.
, p. 1437 - 1443 (2008/10/08)
The proton NMR spectra of iron(II) monohalide complexes of N-methyltetraphenylporphyrin and N-methyloctaethylporphyrin have been recorded and assigned by means of specific deuteration, methyl substitution, intensity, and line width considerations. The N-methyl resonance appears at a characteristic position at 68-145 ppm and is particularly readily observed by 2H NMR spectroscopy on deuterium-labeled samples. The 1H NMR spectra of the iron(II) porphyrin complex bearing an N-CH=C(p-C6H4Cl)2 substituent and the iron(III) porphyrin complex with a C=C(P-C6H4Cl)2 unit inserted into one Fe-N bond are distinct although both spectra are consistent with C3 symmetry for their respective complexes. Imidazole replaces the axial halide ligand to produce derivatives that give clearly resolved resonances of the coordinated amine at -50°C. Both the N-methyl and the histidine N-H resonances should be readily detected and assigned in proteins containing iron(II) N-methylporphyrin.
