95703-26-7Relevant articles and documents
Modular synthesis of sulfonyl benzoheteroles by silver-catalyzed heteroaromatization of propargylic alcohols with p -toluenesulfonylmethyl isocyanide (TosMIC): Dual roles of TosMIC
Liu, Jianquan,Liu, Zhenhua,Liao, Peiqiu,Bi, Xihe
, p. 6204 - 6207 (2014)
A new silver-catalyzed heteroaromatization of propargylic alcohols with p-toluenesulfonylmethyl isocyanide (TosMIC) has been developed that provides an efficient and modular approach to sulfonyl benzoheteroles. For the first time, TosMIC plays a dual role in one reaction: sulfonyl source and ligand. An unprecedented deoxysulfonylation/hydration/condensation reaction pathway is disclosed.
Catalytic oxidation synthesis method of 2-diaryl methyl benzofuran compound
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Paragraph 0026-0036, (2021/05/29)
The invention discloses a catalytic oxidation synthesis method of a 2-diaryl methyl benzofuran compound, which comprises the following steps: by taking a benzofuran compound and diaryl methane as reaction substrates, FeCl2 as a catalyst and 2,3-dichloro-5,6-dinitrile group-1,4-benzoquinone (DDQ) as an oxidant, heating the reaction substrates in a 1,2-dichloroethane solvent to a certain temperature for reaction; after the reaction is finished, carrying out separation treatment to obtain the 2-diaryl methyl benzofuran compound. According to the synthetic method, the diaryl methane and the benzofuran compound can be directly subjected to a coupling reaction to prepare the 2-diaryl methyl benzofuran compound, and existence of a guiding group is not needed any more.
Facile access to 2,2-diaryl 2: H -chromenes through a palladium-catalyzed cascade reaction of ortho -vinyl bromobenzenes with N -tosylhydrazones
Huang, Xueliang,Yu, Yinghua,Zhang, Heng
supporting information, p. 5115 - 5119 (2020/07/23)
A palladium-catalyzed cascade reaction of ortho-vinyl bromobenzenes with N-tosylhydrazones has been developed, which provides a facile approach to 2,2-disubstituted 2H-chromenes. The migration of palladium from the aryl to vinyl position is crucial, as the in situ produced vinyl palladium intermediate could further react with diazo compounds to generate the reactive species for the sequential annulation. This journal is