95705-20-7

Usage

Uses

Used in Polymer Industry:
1,3,5-tris(benzyloxy)-1,3,5-triazinane-2,4,6-trione is used as a crosslinking agent for the production of epoxy resins and other polymers. Its ability to form covalent bonds with polymer chains enhances the mechanical properties and thermal stability of the resulting materials.
Used in Organic Synthesis:
As a building block in organic synthesis, 1,3,5-tris(benzyloxy)-1,3,5-triazinane-2,4,6-trione is utilized to construct a variety of complex organic compounds. Its unique structure allows for the development of novel molecules with potential applications in various fields.
Used in Pharmaceutical Research:
1,3,5-tris(benzyloxy)-1,3,5-triazinane-2,4,6-trione is employed as a starting material in the synthesis of pharmaceutical compounds. Its potential antioxidant and antitumor properties make it a promising candidate for the development of new drugs and therapeutic agents.
Used in Antioxidant Applications:
In preliminary studies, 1,3,5-tris(benzyloxy)-1,3,5-triazinane-2,4,6-trione has shown antioxidant properties, which can be harnessed to develop products that protect against oxidative stress and related diseases.
Used in Antitumor Applications:
1,3,5-tris(benzyloxy)-1,3,5-triazinane-2,4,6-trione has also demonstrated antitumor potential in early research, indicating its possible use in the development of cancer treatments and therapies. Further studies are required to explore its full potential in this area.

Upstream product

• 730-18-7 N-benzyloxycarbamic acid phenyl ester 
• 2687-43-6 O-benzylhydoxylamine hydrochloride 
• 1885-14-9 phenyl chloroformate 
• 530-62-1 1,1'-carbonyldiimidazole 
• 92289-72-0 imidazole-1-carboxylic acid benzyloxyamide 
• 102-09-0 bis(phenyl) carbonate 
• 622-33-3 N-benzyloxyamine 
• 301651-11-6 N-benzyloxy-1H-benzotriazole-1-carboxamide 

Downstream Products

• 143435-52-3 1N,3N,5N-trihydroxy-1,3,5-triazin-2,4,6[1H,3H,5H]-trione 

Relevant academic research and scientific papers

PROCESS FOR PRODUCTION OF N,N';N''-TRISUBSTITUTED ISOCYANURIC ACIDS

A process produces an N,N',N"-trisubstituted isocyanuric acid represented by following Formula (4): wherein R is a hydroxyl-protecting group, by heating an N-substituted carbamic acid derivative represented by following Formula (1): wherein R has the same

Aerobic oxidation of trimethylbenzenes catalyzed by N,N′,N″-trihydroxyisocyanuric acid (THICA) as a key catalyst

The oxidation of trimethylbenzenes was examined with air or O2 using N,N′,N″-trihydroxyisocyanuric acid (THICA) as a key catalyst. Thus, 1,2,3-, 1,2,4-, and 1,3,5-trimethylbenzenes under air (20 atm) in the presence of THICA (5 mol %), Co(OAc)2 (0.5 mol %), Mn(OAc)2, and ZrO(OAc)2 at 150 °C were oxidized to the corresponding benzenetricarboxylic acids in good yields (81-97%). In the aerobic oxidation of 1,2,4-trimethylbenzene by the THICA/Co(II)/Mn(II) system, remarkable acceleration was observed by adding a very small amount of ZrO(OAc)2 to the reaction system to form 1,2,4-benzenetricarboxylic acid in excellent yield (97%). In contrast, no considerable addition effect was observed in the oxidation of 1,3,5-trimethylbenzene. This aerobic oxidation by the present catalytic system provides an economical and environmentally benign direct method to benzenetricarboxylic acids, which are very important polymer materials.

Development of an efficient method for preparation of 1,3,5- trihydroxyisocyanuric acid (THICA) and its use as aerobic oxidation catalyst

1,3,5-Trihydroxyisocyanuric acid (THICA), which serves as an efficient radical-producing catalyst from hydrocarbons, was successfully prepared by two methods. The reaction of O-benzylhydroxyamine with phenyl chloroformate gave formbenzyloxycarbamic acid phenyl ester of which subsequent treatment with dimethylaminopyridine (DMAP) produced 1,3,5-tribenzyloxyisocyanurate leading to THICA by hydrogenation with H2 on Pd/C. The other method involved the direct synthesis of 1,3,5-tribenzyloxyisocyanurate from O-benzylhydroxyamine and diphenyl carbonate. The aerobic oxidation of p-methylanisole catalyzed using THICA as a key catalyst afforded p-anisic acid in almost quantitative yield (>99%).

CATALYSTS COMPRISING CYCLIC ACYLUREA COMPOUNDS AND PROCESSES FOR PRODUCTION OF ORGANIC COMPOUNDS WITH THE SAME

A catalyst of the invention includes a cyclic acylurea compound having a cyclic acylurea skeleton represented by following Formula (I): wherein R is a hydrogen atom or a hydroxyl-protecting group; n is 1 or 2; G is a carbon atom or a nitrogen atom, where two Gs are the same or different when n is 2. The catalyst may include the cyclic acylurea compound and a metallic compound in combination. In the presence of the catalyst, (A) a compound capable of forming a radical is allowed to react with (B) a radical scavenging compound and thereby yields an addition or substitution reaction product of the compound (A) and the compound (B) or a derivative thereof. This catalyst can produce an organic compound with a high selectivity in a high yield as a result of, for example, an addition or substitution reaction under mild conditions.

Oxidation of substituted toluenes with molecular oxygen in the presence of N,N′,N″-Trihydroxyisocyanuric acid as a key catalyst

N,N′,N″-Trihydroxyisocianuric acid (THICA) was found to be a very efficient catalyst for the oxidation of alkylbenzenes with dioxygen. Thus, a variety of meta- and para-substituted toluenes bearing an electron-withdrawing substituent such as cyanotoluene, chlorotoluene, and toluic acid under O2 (1 atm) in the presence of THICA (5 mol %) and Co(OAc)2 (0.5 mol %) at 100 °C were smoothly oxidized to the corresponding benzoic acids in almost quantitative yields. The aerobic oxidation of toluene by THICA was compared with that by N-hydroxyphthalimide. p-Xylene was efficiently oxidized by THICA to telephthalic acid in high yield (over 95%) under mild conditions.

Reactions with 1-benzotriazolecarboxylic acid chloride. VIII. Synthesis of N-hydroxyisocyanate derivatives

1,3,5-Trihydroxy-1,3,5-triazine-2,4,6(1H,3H,5H-)-trione (5), the trimer of hypothetical acid HO-N=C=O, was synthesized by hydrogenolysis of 1,3,5-tribenzyloxy-1,3,5-triazine-2,4,6(1H,3H,5H)-trione (4). Similarly, the 1-(N-hydroxycarbamoyl)benzotriazole (6