957212-53-2Relevant academic research and scientific papers
Design and synthesis of potent inhibitors of cholesteryl ester transfer protein (CETP) exploiting a 1,2,3,4-tetrahydroquinoline platform
Rano, Thomas A.,Sieber-McMaster, Ellen,Pelton, Patricia D.,Yang, Maria,Demarest, Keith T.,Kuo, Gee-Hong
, p. 2456 - 2460 (2009)
Tetrahydroquinoline A is a potent inhibitor of the cholesterol ester transfer protein (CETP), a target for the treatment of low HDL-C and atherosclerosis. Low HDL-C has been identified as a key risk factor for cardiovascular disease in addition to high LD
1,2,3,4-TETRAHYDRO-QUINOLINE DERIVATIVES AS CETP INHIBITORS
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Page/Page column 96, (2008/06/13)
The invention is directed to compounds of Formula (I) described herein useful as CETP inhibitors, compositions containing them, and methods of using them.
