95791-30-3

Upstream product

• 95791-19-8 C₃₀H₄₂O₇Si 
• 95791-20-1 C₃₇H₄₈O₇Si 
• 95791-22-3 C₂₁H₂₈O₇ 
• 95791-25-6 C₄₀H₅₄O₁₁S 
• 95791-24-5 C₄₀H₅₆O₁₁S 
• 95791-32-5 C₃₄H₅₀O₉ 
• 95791-22-3 C₂₁H₂₈O₇ 
• 95791-21-2 C₂₁H₃₀O₇ 
• 95791-18-7 C₁₄H₂₄O₇ 
• 95791-32-5 C₃₄H₅₀O₉ 
• 95791-29-0 C₃₄H₅₀O₈ 
• 93635-20-2 (2S,3R,6S)-2-((R)-2-Benzenesulfonyl-1-methyl-ethyl)-3-methyl-1,7-dioxa-spiro[5.5]undecane 
• 95791-25-6 C₄₀H₅₄O₁₁S 
• 95791-24-5 C₄₀H₅₆O₁₁S 

Downstream Products

• 95791-32-5 C₃₄H₅₀O₉ 
• 95791-30-3 C₃₄H₅₂O₉ 

Relevant academic research and scientific papers

SYNTHESIS OF A MARINE POLYETHER TOXIN, OKADAIC ACID (4).TOTAL SYNTHESIS.

Three segments A, B and C for okadaic acid synthesis were coupled with each other in order of A+(B+C), the key steps of the twice couplings being between sulfone carbanions and aldehydes.After the B+C coupling , the asymmetric center C-27 was generated by a hydride reduction of the corresponding ketone 16 under electronic control.The second coupling was followed to form the C-14/15 double bond.Oxidation of the α-oxy aldehyde 36 into the carboxylic acid group was achieved with sodium chlorite without C-1/C-2 bond cleavage.The total synthesis of okadaic acid was accomplished in 106 steps from commercially available D-glucose derivative s and butyne-diol.

Synthetic studies of marine toxic polyethers. 2. Synthesis of the B-segment of okadaic acid and coupling with the C-segment

Part of okadaic acid was synthesized stereoselectively (involving C-16 through C-38 with 10 asymmetric carbons), by coupling the synthetic segments B and C, the former being prepared from a D-glucopyranose derivative.