958462-15-2

Basic information

• Product Name: (3E)-1-benzoyl-3-(dimethylamino)methylidenepyrrolidin-2-one
• Synonyms: (3E)-1-benzoyl-3-(dimethylamino)methylidenepyrrolidin-2-one
• CAS NO: 958462-15-2
• Molecular Weight: 244.293
• Mol File: 958462-15-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3E)-1-benzoyl-3-(dimethylamino)methylidenepyrrolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (3E)-1-benzoyl-3-(dimethylamino)methylidenepyrrolidin-2-one(958462-15-2)
• EPA Substance Registry System: (3E)-1-benzoyl-3-(dimethylamino)methylidenepyrrolidin-2-one(958462-15-2)

Safety Data

• Hazardous Substances Data: 958462-15-2(Hazardous Substances Data)

Upstream product

• 2399-66-8 1-benzoylpyrrolidin-2-one 
• 5815-08-7 tert-Butoxybis(dimethylamino)methane 
• 98-88-4 benzoyl chloride 

Downstream Products

• 958462-26-5 N-[2-(5-hydroxy-1-phenyl-1H-pyrazol-4-yl)ethyl]benzamide 
• 958462-27-6 4-[4-(2-benzamidoethyl)-5-hydroxy-1H-pyrazol-1-yl]benzoic acid 
• 958462-28-7 N-{2-[1-(3-chlorophenyl)-5-hydroxy-1H-pyrazol-4-yl]ethyl}benzamide 
• 958462-29-8 N-{2-[1-(4-chlorophenyl)-5-hydroxy-1H-pyrazol-4-yl]ethyl}benzamide 
• 958462-30-1 N-{2-[5-hydroxy-1-(3-methoxyphenyl)-1H-pyrazol-4-yl]ethyl}benzamide 
• 958462-31-2 N-{2-[5-hydroxy-1-(4-methoxyphenyl)-1H-pyrazol-4-yl]ethyl}benzamide 
• 958462-32-3 N-{2-[3-oxo-2-(pyridin-2-yl)-2,3-dihydro-1H-pyrazol-4-yl]ethyl}benzamide 
• 958462-33-4 N-{2-[2-(6-chloropyridazin-3-yl)-3-oxo-2,3-dihydro-1H-pyrazol-4-yl]ethyl}benzamide 
• 958462-34-5 N-{2-[3-oxo-2-(6-phenylpyridazin-3-yl)-2,3-dihydro-1H-pyrazol-4-yl]ethyl}benzamide 
• 958462-35-6 N-{2-[2-(imidazo[1,2-b]pyridazin-6-yl)-3-oxo-2,3-dihydro-1H-pyrazol-4-yl]ethyl}benzamide 
• 958462-21-0 N-[2-(5-hydroxy-1H-pyrazol-4-yl)ethyl]benzamide 
• 958462-22-1 N-[2-(5-hydroxy-1-methyl-1H-pyrazol-4-yl)ethyl]benzamide 
• 958462-23-2 N-{2-[5-hydroxy-1-(2,2,2-trifluoroethyl)-1H-pyrazol-4-yl]ethyl}benzamide 
• 958462-24-3 N-[2-(1-benzyl-5-hydroxy-1H-pyrazol-4-yl)ethyl]benzamide 

Relevant articles and documents

A simple synthesis of 4-(2-aminoethyl)-5-hydroxy-1H-pyrazoles

A simple four-step synthesis of 4-(2-aminoethyl)-5-hydroxy-1H-pyrazoles 8 (or their 1H-pyrazol-3(2H)-one tautomers 8′) as the pyrazole analogues of histamine was developed. First, enamino lactam 3 was prepared as the key intermediate in two steps from 2-p