958651-46-2 Usage
Uses
Used in Pharmaceutical Industry:
4-Bromo-N-tert-butyl-3-methylbenzenesulfonamide is used as a building block for the development of drugs, particularly those targeting carbonic anhydrase enzymes. Its inhibitory action on these enzymes makes it a promising candidate for treating conditions such as glaucoma and epilepsy, where modulation of carbonic anhydrase activity can help manage symptoms and improve patient outcomes.
Used in Organic Synthesis:
As a reagent in organic synthesis, 4-Bromo-N-tert-butyl-3-methylbenzenesulfonamide is employed to facilitate the creation of various organic compounds. Its unique structure, which includes a bromine atom, allows for a range of synthetic reactions that can lead to the formation of new molecules with diverse applications across different industries.
Used in Research and Development:
4-Bromo-N-tert-butyl-3-methylbenzenesulfonamide is also utilized in research and development settings, where its properties and reactivity are studied to explore new applications and improve existing synthetic methods. This can lead to advancements in the fields of chemistry and medicine, as well as the discovery of new compounds with potential therapeutic uses.
Check Digit Verification of cas no
The CAS Registry Mumber 958651-46-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,5,8,6,5 and 1 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 958651-46:
(8*9)+(7*5)+(6*8)+(5*6)+(4*5)+(3*1)+(2*4)+(1*6)=222
222 % 10 = 2
So 958651-46-2 is a valid CAS Registry Number.
958651-46-2Relevant academic research and scientific papers
Sulfonylureido thiazoles as fructose-1,6-bisphosphatase inhibitors for the treatment of Type-2 diabetes
Kitas, Eric,Mohr, Peter,Kuhn, Bernd,Hebeisen, Paul,Wessel, Hans Peter,Haap, Wolfgang,Ruf, Armin,Benz, Joerg,Joseph, Catherine,Huber, Walter,Sanchez, Ruben Alvarez,Paehler, Axel,Benardeau, Agnes,Gubler, Marcel,Schott, Brigitte,Tozzo, Effie
supporting information; experimental part, p. 594 - 599 (2010/05/19)
Sulfonylureido thiazoles were identified from a HTS campaign and optimized through a combination of structure-activity studies, X-ray crystallography and molecular modeling to yield potent inhibitors of fructose-1,6-bisphosphatase. Compound 12 showed favo
2,4,6-TRISUBSTITUTED PYRIDO (3,2-d) PYRIMIDINES USEFUL FOR TREATING VIRAL INFECTIONS
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Page/Page column 74, (2010/04/03)
Pyrido(3,2-d)pyrimidine derivatives represented by the structural formuia (Ia): wherein, R1, R2 and R3 are defined herein, pharmaceutical acceptable addition salts, stereochemical isomeric forms, N-oxides, solvates and pro
New FBPase inhibitors for diabetes
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Page/Page column 18-19, (2008/06/13)
Compounds of formula as well as pharmaceutically acceptable salts and esters thereof, wherein R1 to R3 have the significance given in the application and which can be used in the form of pharmaceutical compositions.
