958859-18-2

Upstream product

• 108-77-0 1,3,5-trichloro-2,4,6-triazine 
• 958859-11-5 2-[N-methyl-N-(2-hydroxyethyl)-4-aminophenyl]benzothiazole 

Downstream Products

• 958859-33-1 10-(3-{3-[4-{2-[(4-benzothiazol-2-yl-phenyl)-methyl-amino]-ethoxy}-6-(2-methyl-benzylamino)-[1,3,5]triazin-2-ylamino]-propionylamino}-propyl)-1,4,7,10-tetraaza-cyclododecane-1,4,7-tricarboxylic acid tri-tert-butyl ester 
• 958859-20-6 10-(3-{2-[4-{2-[(4-benzothiazol-2-yl-phenyl)-methyl-amino]-ethoxy}-6-(4-chloro-benzylamino)-[1,3,5]triazin-2-ylamino]-(S)-propionylamino}-propyl)-1,4,7,10-tetraazacyclododecane-1,4,7-tricarboxylic acid tri-tert-butyl ester 
• 958859-28-4 10-{3-[3-(4-{2-[(4-benzothiazol-2-yl-phenyl)-methyl-amino]-ethoxy}-6-cyclododecylamino-[1,3,5]triazin-2-ylamino)-propionylamino]-propyl}-1,4,7,10-tetraaza-cyclododecane-1,4,7-tricarboxylic acid tri-tert-butyl ester 
• 1021148-92-4 10-[3-(4-{2-[(4-benzothiazol-2-yl-phenyl)-methyl-amino]-ethoxy}-6-butylamino-[1,3,5]triazin-2-ylamino)-propyl]-1,4,7,10-tetraaza-cyclododecane-1,4,7-tricarboxylic acid tri-tert-butyl ester 

Relevant academic research and scientific papers

Cleavage agents for soluble oligomers of amyloid β peptides

(Chemical Equation Presented) Clearing the mind: Peptide-cleaving agents for amyloid β-42 (Aβ42) oligomers (see scheme), the intermediate neurotoxic species in the pathology of Alzheimer's disease, have been obtained from a combinatorial librar

New chelating ligands for Co(III)-based peptide-cleaving catalysts selective for pathogenic proteins of amyloidoses

The Co(III) complex of 1,4,7,10-tetraazacyclododecane has been employed as the catalytic center of target-selective peptide-cleaving catalysts in previous studies. As new chelating ligands for the Co(III) ion in the peptide-cleaving catalysts, 1-oxo-4,7,1

CLEAVAGE AGENT SELECTIVELY ACTING ON SOLUBLE ASSEMBLY OF AMYLOIDOGENIC PEPTIDE OR PROTEIN

The present invention relates to a cleavage agent and a cleavage method selectively acting on soluble assembly of amyloidogenic peptide or protein.

A CLEAVAGE AGENT SELECTIVELY ACTING ON SOLUBLE ASSEMBLY OF AMYLOIDOGENIC PEPTIDE OR PROTEIN

The present invention relates to a cleavage agent and a cleavage method selectively acting on soluble assembly of amyloidogenic peptide or protein.