95926-76-4

Upstream product

• 102147-31-9 tert-butyl cyclohex-2-enyl carbonate 
• 86-93-1 1-Phenyl-1H-tetrazole-5-thiol 
• 51479-76-6 cyclohex-2-en-1-yl 2,2,2-trichloroacetimidate 
• 822-67-3 Cyclohex-2-enol 
• 32276-00-9 S,S-bis(1-phenyl-1H-tetrazol-5-yl) dithiocarbonate 
• 86-93-1 1-phenyl-1H-tetrazole-5-thiol 
• 1521-51-3 rac-3-bromocyclohexene 

Downstream Products

• 37488-68-9 1-(cyclohex-2-en-1-ylsulfonyl)-4-methylbenzene 
• 92-52-4 biphenyl 
• 15232-96-9 3-phenyl-1-cyclohexene 
• 95926-78-6 4-(2-Cyclohexen-1-yl)-1,4-dihydro-1-phenyl-5H-tetrazol-5-thion 
• 95926-82-2 2-Cyclohexen-1-ylphenylcarbodiimid 
• 19386-90-4 N-(2-Cyclohexen-1-yl)-N'-phenylharnstoff 
• 31151-39-0 2-(2'-cyclohexen-1'-yl)-1-oxo-1-phenylethane 

Relevant academic research and scientific papers

Direct Synthesis of Thioethers from Carboxylates and Thiols Catalyzed by FeCl3

A new and efficient method has been developed for the synthesis of thioethers from carboxylates and thiols. The reaction proceeds via a Fe(III)-catalyzed direct displacement of carboxylates from benzylic or allylic esters by heterocyclic thiols. Short rea

Alkylation of thiols with trichloroacetimidates under neutral conditions

Trichloroacetimidates are displaced with thiols to form the corresponding sulfides without the need for an added acid or base by simply heating the reactants in refluxing THF. This operationally simple procedure provides the corresponding sulfides in excellent yields with only the formation of the neutral trichloroacetamide as the side product. The imidate may also be formed in situ, allowing for a direct method for the formation of sulfides from alcohols. This reaction provides a general method for the synthesis of a variety of sulfides from inexpensive and readily available alcohol starting materials.

Ga(OTf)3-catalyzed direct substitution of alcohols with sulfur nucleophiles

It is reported that Ga(OTf)3 catalyzes the direct displacement of alcohols with sulfur nucleophiles. The products are versatile intermediates that can be utilized in carbon - carbon, carbon - sulfur bond formation or used in modified Julia olef

SINGLE-STEP PREPARATION OF ALLYLIC SULFIDES HAVING 1-PHENYLTETRAZOLE-5-THIO GROUP FROM ALLYLIC ALCOHOLS USING S,S'-BIS(1-PHENYL-1H-TETRAZOL-5-YL) DITHIOCARBONATE AND REACTIONS INVOLVING THE ALLYLIC SULFIDES

The reaction of allylic alcohols and S,S'-bis(1-phenyl-1H-tetrazol-5-yl) dithiocarbonate (1) gave allylic sulfides having 1-phenyltetrazole-5-thio group in a single step.Furthermore, these allylic sulfides could be applied to carbon-carbon bond and carbon-sulfur bond formations by using Grignard reagents or carbanions in the presence of catalytic amount of copper(I) bromide or palladium (0), respectively.

Photoextrusion of Nitrogen from 1,4-Dihydro-1-phenyl-5H-tetrazol-5-ones and -thiones. Benzimidazolones and Carbodiimides

Alkylation of 1-phenyltetrazolone 10a with 2-cyclohexen-1-yl bromide followed by dehydrogenation with 2,3-dichloro-5,6-dicyano-1,4-benzoquinone permits introduction of a phenyl group at N-4 of the tetrazole ring via the sequence 10a -> 10f -> 10g.The photoextrusion of molecular nitrogen from the (N-4)-substituted 1-phenyltetrazolones, 10a (hydrogen), 10b (methyl), 10d,e (propenyl), and 10g (phenyl) produces essentially quantitative yields of the corresponding benzimidazolones 14a,b,d,e,g.On irradiation of the 1-phenyltetrazolethiones 8b,f,g the carbodiimides 22b,f,g are obtained together with molecular nitrogen and sulfur, while 8a affords phenylcyanamide (25).In contrast to the thermolysis, which is known to give 2-(methylamino)benzothiazole (21b), photolysis of the (phenylimino)-1,2,3,4-thiatriazole 24, an isomer of methylphenyltetrazolethione 8b, also yields molecular nitrogen, sulfur, and methylphenylcarbodiimide (22b).