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Uridine, 3-benzoyl-2'-deoxy-5-fluoro-3'-O-(phenylmethyl)is a nucleoside derivative of uridine, characterized by the presence of a benzoyl group at the 3 position and a 5-fluoro-3'-O-(phenylmethyl) group. This chemical compound is significant in biological research for its potential to elucidate the impact of structural modifications on the biological activity of uridine. Its unique structure may also render it valuable in the realms of drug development and therapeutic applications.

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  • 95969-81-6 Structure
  • Basic information

    1. Product Name: Uridine, 3-benzoyl-2'-deoxy-5-fluoro-3'-O-(phenylmethyl)-
    2. Synonyms:
    3. CAS NO:95969-81-6
    4. Molecular Formula: C23H21FN2O6
    5. Molecular Weight: 440.428
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 95969-81-6.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: Uridine, 3-benzoyl-2'-deoxy-5-fluoro-3'-O-(phenylmethyl)-(CAS DataBase Reference)
    10. NIST Chemistry Reference: Uridine, 3-benzoyl-2'-deoxy-5-fluoro-3'-O-(phenylmethyl)-(95969-81-6)
    11. EPA Substance Registry System: Uridine, 3-benzoyl-2'-deoxy-5-fluoro-3'-O-(phenylmethyl)-(95969-81-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 95969-81-6(Hazardous Substances Data)

95969-81-6 Usage

Uses

Used in Pharmaceutical Research and Development:
Uridine, 3-benzoyl-2'-deoxy-5-fluoro-3'-O-(phenylmethyl)is utilized as a research tool in pharmaceutical research to investigate the effects of structural alterations on the biological activity of nucleosides. This can aid in the discovery of novel drug candidates with improved efficacy and selectivity.
Used in Therapeutic Applications:
In the therapeutic industry, Uridine, 3-benzoyl-2'-deoxy-5-fluoro-3'-O-(phenylmethyl)may serve as a precursor or modulator of biological processes, given its structural resemblance to naturally occurring nucleosides. Its potential applications could include the treatment of diseases where nucleoside metabolism is implicated, such as certain genetic disorders or viral infections.
Used in Biochemical Studies:
Uridine, 3-benzoyl-2'-deoxy-5-fluoro-3'-O-(phenylmethyl)is also employed in biochemical studies to understand the role of nucleosides in cellular processes. By examining the interactions of Uridine, 3-benzoyl-2'-deoxy-5-fluoro-3'-O-(phenylmethyl)with enzymes and other biomolecules, researchers can gain insights into the mechanisms of nucleoside metabolism and its regulation.
Used in Drug Synthesis:
In the field of drug synthesis, Uridine, 3-benzoyl-2'-deoxy-5-fluoro-3'-O-(phenylmethyl)could be a key intermediate in the production of new pharmaceuticals. Its unique functional groups may allow for the creation of drugs with specific targeting or activity profiles, enhancing the therapeutic arsenal against various diseases.

Check Digit Verification of cas no

The CAS Registry Mumber 95969-81-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,5,9,6 and 9 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 95969-81:
(7*9)+(6*5)+(5*9)+(4*6)+(3*9)+(2*8)+(1*1)=206
206 % 10 = 6
So 95969-81-6 is a valid CAS Registry Number.

95969-81-6Relevant articles and documents

5-fluorouracil derivatives

-

, (2008/06/13)

An anticancer compound is disclosed which is represented by the formula STR1 wherein one of R1 and R2 is a phenyl-lower alkyl optionally having a substituent, phenyl-lower alkenyl or naphthyl-lower alkyl, the other of R1 and R2 is hydrogen or acyl, and R3 is hydrogen, acyl or tetrahydrofuranyl, or represented by the formula STR2 wherein Rx is an optionally substituted pyridyl, Y is arylene and α is a known 5-fluorouracil derivative residue which can be converted to 5-fluorouracil in vivo and which is linked to the carbonyl by an ester or amide linkage.

Studies on antitumor agents. 8. Antitumor activities of O-alkyl derivatives of 2'-deoxy-5-(trifluoromethyl)uridine and 2'-deoxy-5-fluorouridine

Yamashita,Takeda,Matsumoto,Unemi,Yasumoto

, p. 136 - 139 (2007/10/02)

O-Benzyl and O-ethyl derivatives of 2'-deoxy-5-(trifluoromethyl)uridine (F3Thd) and 2'-deoxy-5-fluorouridine (FUdR) were synthesized. The oral antitumor activity of the compounds against sarcoma 180 in mice was examined. The 5'-O-ethyl (3b), 3'

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