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Imidazo[1,5-a]pyrido[3,2-e]pyrazine, 2-methoxy-6,7-dimethyl-9-propyl-, also known as TC-E 5005, is a chemical compound with a unique structure that features a fused imidazo and pyrido ring system. It is characterized by the presence of a methoxy group at the 2nd position, and methyl and propyl groups at the 6th, 7th, and 9th positions, respectively. Imidazo[1,5-a]pyrido[3,2-e]pyrazine, 2-methoxy-6,7-dimethyl-9-propylhas been identified for its potential applications in various fields due to its specific properties.

959705-64-7

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959705-64-7 Usage

Uses

Used in Pharmaceutical Industry:
Imidazo[1,5-a]pyrido[3,2-e]pyrazine, 2-methoxy-6,7-dimethyl-9-propylis used as a phosphodiesterase 10 selective inhibitor for the treatment of benign prostatic hyperplasia (BPH). As a PDE10 inhibitor, it helps in reducing adrenergic and non-adrenergic smooth muscle contractions in the human prostate, which can alleviate symptoms associated with BPH and improve urinary flow.
Imidazo[1,5-a]pyrido[3,2-e]pyrazine, 2-methoxy-6,7-dimethyl-9-propyl-'s selectivity for PDE10 over other phosphodiesterase enzymes makes it a promising candidate for targeted therapies with potentially fewer side effects compared to non-selective inhibitors. Further research and development are necessary to fully understand the therapeutic potential of Imidazo[1,5-a]pyrido[3,2-e]pyrazine, 2-methoxy-6,7-dimethyl-9-propyland to explore additional applications in various medical fields.

Check Digit Verification of cas no

The CAS Registry Mumber 959705-64-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,5,9,7,0 and 5 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 959705-64:
(8*9)+(7*5)+(6*9)+(5*7)+(4*0)+(3*5)+(2*6)+(1*4)=227
227 % 10 = 7
So 959705-64-7 is a valid CAS Registry Number.

959705-64-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Methoxy-6,7-dimethyl-9-propylimidazo[1,5-a]pyrido[3,2-e]pyrazin e

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

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More Details:959705-64-7 SDS

959705-64-7Downstream Products

959705-64-7Relevant academic research and scientific papers

Discovery of imidazo[1,5-a]pyrido[3,2-e]pyrazines as a new class of phosphodiesterase 10A inhibitiors

H?fgen, Norbert,Stange, Hans,Schindler, Rudolf,Lankau, Hans-Joachim,Grunwald, Christian,Langen, Barbara,Egerland, Ute,Tremmel, Peter,Pangalos, Menelas N.,Marquis, Karen L.,Hage, Thorsten,Harrison, Boyd L.,Malamas, Michael S.,Brandon, Nicholas J.,Kronbach, Thomas

supporting information; experimental part, p. 4399 - 4411 (2010/08/06)

Novel imidazo[1,5-a]pyrido[3,2-e]pyrazines have been synthesized and characterized as both potent and selective phosphodiesterase 10A (PDE10A) inhibitors. For in vitro characterization, inhibition of PDE10A mediated cAMP hydrolysis was used and a QSAR mod

PYRIDO[3,2-e]PYRAZINES, THEIR USE AS INHIBITORS OF PHOSPHODIESTERASE 10, AND PROCESSES FOR PREPARING THEM

-

, (2008/06/13)

The invention relates to pyrido[3,2-e]pyrazines, to processes for preparing them, to pharmaceutical preparations which comprise these compounds and to the pharmaceutical use of these compounds, which are inhibitors of phosphodiesterase 10, as active compounds for treating diseases of mammals including a human which can be influenced by using the compounds according to the invention to inhibit phosphodiesterase 10 activity in the central nervous system. More particularly, the invention relates to the treatment of neurologic and psychiatric disorders, for example psychosis and disorders comprising cognitive deficits as symptoms.

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