960148-65-6

Upstream product

• 3282-30-2 pivaloyl chloride 
• 132606-95-2 (2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)tetrahydrofuran-3-yl hydrogen phosphonate 

Downstream Products

• 917480-85-4 C₁₀H₁₃N₅O₄SiC₆H₁₄PO₃HC(C₆H₅)3C₁₁H₁₁O₂ 

Relevant academic research and scientific papers

Stereochemistry of internucleotide bond formation by the H-phosphonate method. 1. Synthesis and 31P NMR analysis of 16 diribonulceoside (3′-5′)-H-phosphonates and the corresponding phosphorothioates

□ Sixteen diribonucleoside (3′-5′)-H-phosphonates were synthesized via condensation of the protected ribonucleoside 3′-H-phosphonates with nucleosides, and the influence of a nucleoside sequence on the observed stereoselectivity was analyzed. 31/sup

Stereochemistry of internucleotide bond formation by the H-phosphonate method. Part 3: Investigations on a mechanism of asymmetric induction

The stereochemistry of H-phosphonate diester bond formation (including internucleotide ones) with ribonucleoside H-phosphonates as substrates has been investigated using 31P NMR spectroscopy. It was found that the reactions investigated owe the