960155-97-9Relevant academic research and scientific papers
Synthetic copolymer conjugates of docetaxel and: In vitro assessment of anticancer efficacy
Boyer, Cyrille A.,Clemons, Tristan D.,Edwards, Sky,Evans, Cameron W.,Iyer, K. Swaminathan,Kretzmann, Jessica A.,Nealon, Gareth L.,Norret, Marck,Singh, Ruhani
, p. 20013 - 20020 (2020)
Docetaxel (DTX) is a widely used chemotherapy drug that is associated with numerous side effects and limited bioavailability. Macromolecular conjugates of DTX may improve drug targeting, solubility, reduce off-target toxicity, and overcome mechanisms of m
Salutaxel, a Conjugate of Docetaxel and a Muramyl Dipeptide (MDP) Analogue, Acts as Multifunctional Prodrug That Inhibits Tumor Growth and Metastasis
Wen, Xiaoming,Zheng, Purong,Ma, Yao,Ou, Yingye,Huang, Weixin,Li, Shuo,Liu, Shoujia,Zhang, Xuan,Wang, Ziyu,Zhang, Qianli,Cheng, Wenming,Lin, Ruwen,Li, Hongzu,Cai, Youyou,Hu, Chunyun,Wu, Ningbin,Wan, Long,Pan, Tingting,Rao, Jinlong,Bei, Xuelu,Wu, Weibin,Jin, Jian,Yan, Jie,Liu, Gang
, p. 1519 - 1540 (2018)
Salutaxel (3) is a conjugate of docetaxel (7) and a muramyl dipeptide (MDP) analogue. Docetaxel (7) has been recognized as a highly active chemotherapeutic agent against various cancers. MDP and its analogues are powerful potentiators of the antitumor act
TRANSMUCOSAL DELIVERY OF PHARMACEUTICAL ACTIVE SUBSTANCES
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Page/Page column 13, (2010/11/29)
Provided is a conjugate including a pharmacologically active substance covalently bound to chitosan or its derivative and a method for transmucosal delivery of a pharmacologically active substance using the same. Specifically, a conjugate includes a pharm
