96042-90-9Relevant academic research and scientific papers
2-Oxoglutarate analogue inhibitors of prolyl hydroxylase domain 2
Mecinovic, Jasmin,Loenarz, Christoph,Chowdhury, Rasheduzzaman,Schofield, Christopher J.
supporting information; experimental part, p. 6192 - 6195 (2010/06/13)
Analogues of the 2-oxoglutarate cosubstrate of the human oxygen sensing enzyme prolyl hydroxylase domain 2 (PHD2) with variations in the potential iron-chelating group were screened as inhibitors and for binding (using non-denaturing electrospray ionization mass spectrometry) to PHD2.
UNE NOUVELLE METHODE DE SYNTHESE PEPTIDIQUE INTRAMOLECULAIRE, APPLICABLE A LA SARCOSINE, A L'AIDE DE DERIVES DE L'ACIDE OXALIQUE
Mulliez, Michel,Royer, Jacques
, p. 5143 - 5152 (2007/10/02)
Two steps are postulated in a new method of intramolecular peptide synthesis using oxalic acid derivates (Fig. 1).Both are verified with model derivatives incorporating one sarcosine residue: cyclisation of 2d into 5 (Fig. 4) and aminolysis of 5 leading t
