960595-22-6Relevant articles and documents
Enantioselective construction of quaternary stereogenic carbon atoms by the lewis base catalyzed additions of silyl ketene imines to aldehydes
Denmark, Scott E.,Wilson, Tyler W.,Burk, Matthew T.
supporting information, p. 9268 - 9279 (2014/08/05)
Silyl ketene imines derived from a variety of α-branched nitriles have been developed as highly useful reagents for the construction of quaternary stereogenic centers via the aldol addition reaction. In the presence of SiCl4 and the catalytic a