96221-84-0 Usage
Uses
Used in Pharmaceutical Industry:
1-(2-BENZYLOXY-PHENYL)-PIPERAZINE DIHYDROCHLORIDE is used as a pharmaceutical intermediate for the synthesis of various drugs, primarily targeting neurological and psychiatric disorders. Its unique structure allows for the development of compounds with potential therapeutic effects on these conditions.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 1-(2-BENZYLOXY-PHENYL)-PIPERAZINE DIHYDROCHLORIDE serves as a key building block in the design and synthesis of novel drug candidates. Its versatile chemical structure enables the creation of a wide range of pharmaceuticals with potential applications in treating various diseases and disorders.
Used in Material Science:
1-(2-BENZYLOXY-PHENYL)-PIPERAZINE DIHYDROCHLORIDE may also find applications in material science, where its unique properties could be harnessed to develop new materials with specific characteristics, such as improved stability or reactivity.
Used in Agrochemicals:
In the agrochemical industry, 1-(2-BENZYLOXY-PHENYL)-PIPERAZINE DIHYDROCHLORIDE could be utilized in the development of new compounds for pest control or crop protection, leveraging its chemical properties to create effective and environmentally friendly solutions.
Check Digit Verification of cas no
The CAS Registry Mumber 96221-84-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,6,2,2 and 1 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 96221-84:
(7*9)+(6*6)+(5*2)+(4*2)+(3*1)+(2*8)+(1*4)=140
140 % 10 = 0
So 96221-84-0 is a valid CAS Registry Number.
96221-84-0Relevant academic research and scientific papers
Synthesis and evaluation of a novel class Hsp90 inhibitors containing 1-phenylpiperazine scaffold
Jia, Jian-Min,Liu, Fang,Xu, Xiao-Li,Guo, Xiao-Ke,Jiang, Fen,Cherfaoui, Bahidja,Sun, Hao-Peng,You, Qi-Dong
, p. 1557 - 1561 (2014/03/21)
Previously, we identified 1-(2-(4-bromophenoxy)ethoxy)-3-(4-(2- methoxyphenyl)piperazin-1-yl)propan-2-ol (1) as a novel Hsp90 inhibitor with moderate activity through virtual screening. In this study, we report the optimization process of 1. A series of analogues containing the 1-phenylpiperazine core scaffold were synthesized and evaluated. The structure-activity relationships (SAR) for these compounds was also discussed for further molecular design. This effort afforded the most active inhibitor 13f with improved activity in not only target-based level, but also cell-based level compared with the original hit 1.
