96236-88-3Relevant academic research and scientific papers
THE FORMATION AND METABOLISM OF n-HYDROXYMETHYL COMPOUNDS. PART 6.1 THE SYNTHESIS OF S-AMIDOMETHYL-, S-UREIDOMETHYL-, AND S-(1,3,5-TRIAZIN-2-YLAMINOMETHYL)-GLUTATHIONE DERIVATIVES
Addison, Sally J.,Cunningham, Bernadette D. M.,Gate, E. Nicholas,Shah, Prakash Z.,Threadgill, Michael D.
, p. 75 - 80 (2007/10/02)
Treatment of N-hydroxymethyl and N-alkoxymethyl compounds with glutathione or N-acetylcysteine in trifluoroacetic acid affords the corresponding glutathione or N-acetylcysteine derivatives in high yield.Alkoxymethylureas are formed by the condensation of ureas with formaldehyde and alcohols under basic conditions; the implications of this observation are discussed with reference to possible biochemical mechanisms.
