96259-44-8Relevant academic research and scientific papers
PYRIMIDINE DERIVATIVES AND THEIR USE USE FOR THE TREATMENT OF CANCER
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, (2019/07/13)
Compounds of general formula (I): (Formula (I)) wherein R1, R2, X1 and X2 are as defined herein are useful for the treatment of cancer, particularly solid tumours.
1,2,4-TRIAZINE-6-CARBOXAMIDE KINASE INHIBITORS
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Paragraph 0247, (2014/01/09)
Provided are triazine compounds for inhibiting of Syk kinase, intermediates used in making such compounds, methods for their preparation, pharmaceutical compositions thereof, methods for inhibiting Syk kinase activity, and methods for treating conditions mediated at least in part by Syk kinase activity.
FUNGICIDES BASED ON NITROGEN-CONTAINING HETEROCYCLES
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Page 79, (2008/06/13)
Fungicidal compounds having the general formula (1): formula (1) wherein W, Z and one of X and Y are N and the other one of X and Y is CR8; R8 is H, halo, C1-4 alkyl, C1-4 alkoxy, C1-4 alkylthio or ha
Pyridotriazines and pyridopyridazines
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Page 13, 15, (2010/01/31)
This invention relates to bicyclic heterocycles that inhibit cyclin-dependent kinase or tyrosine kinase enzymes, or both, and as such are useful to treat cell proliferative disorders such as angiogenesis, atherosclerosis, restenosis, and cancer as well as immunological disorders such as asthma, rheumatoid arthritis, autoimmune diabetes, and graft rejection associated with transplant surgery in mammals.
Synthesis of Fused 1,2,4-Triazines: 6- and 7-Azapteridine and 6-Azapurine Ring Systems
Huang, Jim J.
, p. 2293 - 2298 (2007/10/02)
The reaction of diethyl oxomalonate with S-methylisothiosemicarbazide under basic condition was found to give 3-(methylthio)-5-oxo-6-carbethoxy-4,5-dihydro-1,2,4-triazine (1) and 3-(methylthio)-5-carbethoxy-6-oxo-1,6-dihydro-1,2,4-triazine (2).While via 1
