96440-30-1

Upstream product

• 18732-50-8 3-(2'-hydroxyphenyl)-5-phenylisoxazole 
• 79-11-8 chloroacetic acid 
• 98-86-2 acetophenone 
• 90-02-8 salicylaldehyde 
• 644-78-0 2-hydroxychalcone 
• 96440-31-2 ethyl <2-(5-phenyl-3-isoxazolyl)-phenoxy> acetate 
• 1469-94-9 1-(2-hydroxyphenyl)-3-phenyl-1,3-propanedione 

Downstream Products

• 96440-25-4 [2-(5-Phenyl-isoxazol-3-yl)-phenoxy]-acetic acid 3-hydroxy-2-{3-oxo-4-[2-(5-phenyl-isoxazol-3-yl)-phenoxy]-butyryl}-5-{2-[2-(5-phenyl-isoxazol-3-yl)-phenoxy]-acetoxy}-phenyl ester 
• 96440-23-2 1-(2-Hydroxy-phenyl)-4-[2-(5-phenyl-isoxazol-3-yl)-phenoxy]-butane-1,3-dione 
• 96452-36-7 2,4,6-tri-<5-phenyl-3-(2-phenoxyacetyloxy)isoxazole> acetophenone 
• 96440-27-6 2,4-di-<5-phenyl-3-(2-phenoxyacetyloxy)isoxazole> acetophenone 
• 96440-26-5 2-<5-phenyl-3-(2-phenoxyacetyloxy)isoxazole> acetophenone 

Relevant academic research and scientific papers

Synthesis and in-vivo hypolipidemic activity of some novel substituted phenyl isoxazol phenoxy acetic acid derivatives

The present study was undertaken to evaluate in-vivo hypolipidemic activity of a novel series of 2-methyl-2-(substituted phenyl isoxazol)phenoxyacetic acid derivatives by triton induced hyperlipidemia in rats. The newly synthesized compounds 5a, 5d and 5g showed significant decrease in the serum TCH, TG, LDL and VLDL along with an increase in serum HDL levels as compared to standard drug Fenofibrate. The treated groups also showed significant decrease in the atherogenic index and increase in % protective activity compared to control group.

Synthesis of Some New 2--4H-1-benzopyran-4-ones

The synthesis of a few new 4H-1-benzopyran-4-ones having substituents containing heterocyclic systems starting from -acetic acid and 2-hydroxy, 2,4-dihydroxy, 2,4,6-trihydroxy acetophenones has been described.