96454-73-8

Upstream product

• 18720-35-9 bicyclo[2.2.2]octane-1,4-dicarboxylic acid monomethyl ester 
• 2064-05-3 bicyclo<2.2.2>octane-1-carboxaldehyde 
• 90965-06-3 dimethyl 1-(1-diazo-2-oxopropyl)phosphonate 
• 699-55-8 bicyclo[2.2.2]octane-1-carboxylic acid 
• 96454-91-0 1-vinylbicyclo<2.2.2>octane 
• 2574-42-7 1-(hydroxymethyl)bicyclo<2.2.2>octane 
• 105858-43-3 1-(1,2-dibromoethyl)bicyclo<2.2.2>octane 

Relevant academic research and scientific papers

OXAZOLIDINONES AS MODULATORS OF MGLUR5

The disclosure generally relates to compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds are ligands, agonists and partial agonists for the mGluR5 receptor and may be useful for the treatment of various disorders of the central nervous system.

Synthesis and PE Spectra of 1-Ethynyl- and 1,4-Diethynylbicyclooctane, and of Related 1,4-Dihalobicyclooctanes

The synthesis of 1-ethynylbicyclooctane (1), of 1,4-diethynylbicyclooctane (2), of 1,4-dichloro- (3) and of 1,4-dibromobicyclooctane (4) is reported.The He(1α) photoelectron spectra of 1 and 2 have been assigned using the STO-3G and the HAM/3 procedure, whereas those of 3 and 4 have been interpreted on the basis of an equivalent bond orbital model including spin-orbit coupling.