96516-29-9

Basic information

• Product Name: 2-FLUORO-3-NITROBENZALDEHYDE
• Synonyms: 2-FLUORO-3-NITROBENZALDEHYDE
• CAS NO: 96516-29-9
• Molecular Formula: C₇H₄FNO₃
• Molecular Weight: 169.1099632
• Product Categories: Aromatic Aldehydes & Derivatives (substituted);Fluorine series
• Mol File: 96516-29-9.mol

Chemical Properties

• Boiling Point: 279℃
• Flash Point: 122℃
• Appearance: /
• Density: 1.443
• Vapor Pressure: 0.004mmHg at 25°C
• Refractive Index: 1.59
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2-FLUORO-3-NITROBENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-FLUORO-3-NITROBENZALDEHYDE(96516-29-9)
• EPA Substance Registry System: 2-FLUORO-3-NITROBENZALDEHYDE(96516-29-9)

Safety Data

• Hazardous Substances Data: 96516-29-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-Fluoro-3-Nitrobenzaldehyde is utilized as a key intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Fluoro-3-Nitrobenzaldehyde is employed as a precursor in the production of agrochemicals, which are essential for enhancing crop protection and yield.
Used in Dye Industry:
2-Fluoro-3-Nitrobenzaldehyde serves as a crucial component in the creation of dyes, where its unique structure contributes to the color and properties of the final product.
Used as a Fluorescent Probe in Environmental Analysis:
2-Fluoro-3-Nitrobenzaldehyde has demonstrated its potential as a fluorescent probe for detecting heavy metal ions in environmental samples, offering a valuable tool for environmental monitoring and protection.

InChI:InChI=1/C7H4FNO3/c8-7-5(4-10)2-1-3-6(7)9(11)12/h1-4H

Upstream product

• 446-52-6 2-Fluorobenzaldehyde 
• 3970-40-9 2-chloro-3-nitrotoluene 
• 58755-57-0 2-chloro-3-nitrobenzaldehyde 

Downstream Products

• 942224-53-5 tert-butyl 4-(3-amino-2-fluorobenzyl)piperazine-1-carboxylate 
• 1784796-42-4 3-(difluoromethyl)-2-fluoroaniline 

Relevant articles and documents

CONDENSED BI-HETEROCYCLES AS INHIBITING AGENTS FOR BRUTON'S TYROSINE KINASE

Provided are compounds of Formula (I): Formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, A1, B1, B2, Q1 and Q2 are as defined herein; and methods for their use and production.

INHIBITING AGENTS FOR BRUTON'S TYROSINE KINASE

Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, methods for use as Bruton's tyrosine kinase and methods of production.

Nitration of Strongly Deactivated Aromatics with Superacidic Mixed Nitric-Triflatoboric Acid (HNO3/2CF3SO3H-B(O3SCF3)3)

The nitration of various deactivated arenes (including methanesulfonyl-, nitro-, and polyhalobenzenes) was carried out in good yield with mixed nitric-triflatoboric superacid.For example pentafluorobenzene gave pentafluoronitrobenzene in 99percent yield, nitrobenzene to m-dinitrobenzene in 92percent selectivity with 85percent overall yield, and methyl phenyl sulfone gave only the m-nitro isomer in 78percent isolated yield.Thus the new nitrating system gives high regioselectivity and yields under generally mild reaction conditions.The reagent system is compatible with many functional groups of arenes.

Synthesis and antihypertensive activity of 1,4-dihydropyridine derivatives with a 4-(disubstituted phenyl) ring and an aminoalkyl ester group: Highly potent and long-lasting calcium antagonists

New 1,4-dihydropyridine derivatives bearing a 4-(disubstituted phenyl) ring and an aminoethyl ester or an amino-2,2-dimethylpropyl ester were synthesized and their antihypertensive activities were examined in normotensive rats and spontaneously hypertensi