96517-70-3

Upstream product

• 78564-23-5 6-methyl-4-phenyl-2-thioxo-1,2-dihydropyridine-3-carbonitrile 
• 105-39-5 chloroacetic acid ethyl ester 
• 93-91-4 1-phenylbutan-1,3-dione 

Downstream Products

• 148946-35-4 3-Amino-6-methyl-4-phenyl-thieno[2,3-b]pyridine-2-carboxylic acid isopropyl ester 
• 94638-95-6 3-Amino-6-methyl-4-phenyl-thieno<2,3-b>pyridin-2-carbonsaeureethylester 

Relevant academic research and scientific papers

Synthesis of N-(2-carboxy-thieno[2,3-b]pyridine-3-yl)-formamidines and corresponding alkyl esters with antianaphylactic activity

A lot of N-(2-carboxy-thieno[2,3-b]pyridin-3-yl)formamidines especially in form of their amine salts - were synthesized by reaction of 3-amino-thieno[2,3-b]pyridine-2-carboxylic acids with dimethylformamide/phosphoroxide chloride or by reaction of 4-oxo-4 H-pyrido[3',2':4,5]thieno[3,2-d]1,3-oxazines with amines. Carboxylic acid alkylesters of this structure were yielded from 3-amino-thieno[2,3-b]pyridine-2-carbonic acid alkylesters by reaction with dimethylformamide/phosphoroxide chloride or with N-formyl-piperidine or N-formyl-morpholine and phosphoroxide chloride. The compounds showed antianaphylactic activity.