96561-04-5

Basic information

• Product Name: BOC-D-LYS(TFA)-OH
• Synonyms: BOC-D-LYSINE(TFA)-OH;BOC-D-LYS(TFA)-OH;BOC-N-EPSILON-TFA-D-LYSINE;BOC-N-EPSILON-TRIFLUOROACETYL-D-LYSINE;N-ALPHA-T-BUTOXYCARBONYL-N-EPSILON-TRIFLUOROACETYL-D-LYSINE;BOC-N-E-TFA-D-LYSINE;N2-Boc-N6-(Trifluoroacetyl)-D-lysine;(R)-2-((tert-Butoxycarbonyl)aMino)-6-(2,2,2-trifluoroacetaMido)hexanoic acid
• CAS NO: 96561-04-5
• Molecular Formula: C₁₃H₂₁F₃N₂O₅
• Molecular Weight: 342.31
• Mol File: 96561-04-5.mol
• Article Data: 5

Chemical Properties

• Appearance: /Solid
• Storage Temp.: -15°C
• CAS DataBase Reference: BOC-D-LYS(TFA)-OH(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-D-LYS(TFA)-OH(96561-04-5)
• EPA Substance Registry System: BOC-D-LYS(TFA)-OH(96561-04-5)

Safety Data

• Hazardous Substances Data: 96561-04-5(Hazardous Substances Data)

Usage

General Description

BOC-D-LYS(TFA)-OH is a chemical compound that consists of a BOC-protected lysine residue with a trifluoroacetic acid (TFA) functional group attached to the amino terminus. The BOC group serves as a protective group for the amine functionality of lysine, which can be removed under specific conditions to expose the amine group for further chemical modifications. The TFA functional group is a carboxylic acid derivative that can facilitate coupling reactions with other molecules in organic synthesis. BOC-D-LYS(TFA)-OH is commonly used in peptide synthesis and can be deprotected to obtain a free amine group for further biochemical studies and peptide conjugations.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 10009-20-8 (S)-6-trifluoroacetylamino-2-aminohexanoic acid 
• 84624-27-1 Boc-Lys(Fmoc)-OH 
• 383-63-1 ethyl trifluoroacetate, 
• 13734-28-6 Boc-Lys-OH 
• 383-64-2 S-ethyl trifluoroacetate 

Downstream Products

• 34695-46-0 N-alpha-BOC-N-epsilon-TFA-lysine succinimidyl ester 
• 1242276-50-1 C₂₇H₃₇F₃N₄O₅ 
• 1375701-67-9 α-N-Boc-ε-N-trifluoroacetyl-lysine-CBT 
• 142846-53-5 Boc-Lys(COCF₃)-Gly-OCH₂Ph 
• 77829-75-5 C₂₀H₂₈F₃N₃O₅ 
• 142824-66-6 Boc-Lys(COCF₃)-Lys(COCF₃)-Gly-OCH₂Ph 

Relevant articles and documents

Control of lysyl oxidase activity through site-specific deuteration of lysine

Lysyl oxidase (LOX) is implicated in several extracellular matrix related disorders, including fibrosis and cancer. Methods of inhibition of LOX in vivo include antibodies, copper sequestration and toxic small molecules such as β-aminopropionitrile. Here,

Synthesis of a radioiodinated park nucleotide analog: A new tool for antibacterial screen development

The Park nucleotide is an important biological building block used in the construction of bacterial cell walls. Herein, we describe the synthesis of a radiolabeled Park nucleotide analog, p-iodophenoxyacyl-Ala-(D)-iso- GluLys-(D)-Ala-(D)-Ala-OH-[125

Tactics for simplification of purification process in the solid phase peptide synthesis.

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