96568-27-3

Upstream product

• 140-88-5 ethyl acrylate 
• 106-45-6 para-thiocresol 
• 114171-56-1 2-chloro-5-fluoro-6-(p-tolylthio)nicotinamide 
• 108108-37-8 2,5-difluoro-6-(p-tolylthio)nicotinamide 
• 96568-24-0 2-chloro-5-fluoro-6-(p-tolylthio)nicotinonitrile 
• 96568-25-1 2,5-difluoro-6-(p-tolylthio)nicotinonitrile 
• 82671-03-2 ethyl 2,6-dichloro-5-fluoropyridine-3-carboxylate 
• 82671-02-1 2,6-dichloro-5-fluoro-pyridine-3-carbonitrile 
• 76731-85-6 β-cyclopropylaminopropionic acid ethyl ester 
• 114171-57-2 ethyl 2-chloro-5-fluoro-6-(p-tolylthio)nicotinate 
• 96568-26-2 ethyl 2,5-difluoro-6-(p-tolylthio)nicotinate 

Downstream Products

• 114171-67-4 1-Cyclopropyl-4-oxo-6-piperidin-1-yl-7-(toluene-4-sulfonyl)-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid ethyl ester 
• 96568-30-8 ethyl 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(p-tolylsulfonyl)-1,8-naphthyridine-3-carboxylate 
• 114171-61-8 ethyl 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(p-tolylsulfinyl)-1,8-naphthyridine-3-carboxylate 
• 96568-29-5 ethyl 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(p-tolylthio)-1,8-naphthyridine-3-carboxylate 
• 98417-05-1 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(p-tolylsulfonyl)-1,8-naphthyridine-3-carboxylic acid 
• 114171-62-9 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(p-tolylsulfinyl)-1,8-naphthyridine-3-carboxylic acid 
• 98417-07-3 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(p-tolylthio)-1,8-naphthyridine-3-carboxylic acid 
• 99735-41-8 ciprofloxacin 
• 114171-71-0 ethyl 1-cyclopropyl-6-fluoro-1,2-dihydro-4-hydroxy-7-(p-tolylthio)-1,8-naphthyridine-3-carboxylate 

Relevant academic research and scientific papers

Antibacterial 7-(3-amino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid derivatives

The present invention relates to a 1,8-naphthyridine derivative of the formula STR1 wherein R1, R2 and R3 are the same or different and each hydrogen or lower alkyl having 1 to 5 carbon atoms; and esters thereof and salts thereof and processes for preparation thereof. These compounds show excellent antibacterial activity and are useful antibacterial agents.