96689-27-9

Upstream product

• 49639-05-6 1-(phenylsulfonyl)-2-methyl-2-propene 
• 873-55-2 sodium benzenesulfonate 
• 156714-06-6 (-)-(S)-4-bromo-3-methylbut-1-ene 
• 96689-26-8 1-hydroxy-2-methyl-3-(phenylsulfonyl)propane 

Downstream Products

• 124292-06-4 2-(2-Benzenesulfonyl-1-methyl-ethyl)-oxirane 
• 112766-68-4 (6Z,10Z,14E,18E,22E)-(R)-4-Benzenesulfonyl-3,7,11,15,19,23,27-heptamethyl-octacosa-6,10,14,18,22,26-hexaen-1-ol 
• 112766-66-2 (6Z,10Z,14E,18E)-(R)-4-Benzenesulfonyl-3,7,11,15,19,23-hexamethyl-tetracosa-6,10,14,18,22-pentaen-1-ol 
• 78505-05-2 (3S)-3-methyl-4-phenylsulfonylbutanol 

Relevant academic research and scientific papers

SYNTHESIS OF DOLICHOL-TYPE (S)-HEXA- AND (S)-HEPTAPRENOLS

(R)-1-Phenylsulfonyl-2-methylbutan-4-ol has been used as starting material for the stepwise synthesis of the dolichol-related hexa- and heptaprenols (S)-3,7,11,15,19,23-hexymethyltetraicosa-6Z,10Z,14E,18E,22-pentaene1-ol and (S)-3,7,-11,15,19,23,27-heptamethyloctaicosa-6Z,10Z,14E,18E,22E,26-hexaen-1-ol.

Stereochemistry of Addition of Organocopper Reagents and of the Hydride Ion to 1-(Arylsulfonyl)bicyclobutanes

Addition of methylmagnesium iodide/cuprous iodide or of lithium dimethylcuprate to 2-exo- and 2-endo-methyl-1-(phenylsulfonyl)bicyclobutane and determination of the relative geometry of the methyls in the 2,3-dimethylcyclobutanes obtained allowed u