967-42-0

Basic information

• Product Name: 1H-Purine-2,6-dione, 3,7-dihydro-8-(4-methoxyphenyl)-1,3-dimethyl-
• CAS NO: 967-42-0
• Molecular Formula: C14H14N4O3
• Molecular Weight: 286.29
• Mol File: 967-42-0.mol

Chemical Properties

• CAS DataBase Reference: 1H-Purine-2,6-dione, 3,7-dihydro-8-(4-methoxyphenyl)-1,3-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Purine-2,6-dione, 3,7-dihydro-8-(4-methoxyphenyl)-1,3-dimethyl-(967-42-0)
• EPA Substance Registry System: 1H-Purine-2,6-dione, 3,7-dihydro-8-(4-methoxyphenyl)-1,3-dimethyl-(967-42-0)

Safety Data

• Hazardous Substances Data: 967-42-0(Hazardous Substances Data)

Usage

Core structure

Purine core
Purines are heterocyclic organic compounds with a double-ring structure consisting of a 6-membered pyrimidine ring fused to a 5-membered imidazole ring.

Oxidation state

1H
The presence of a 1H indicates that the compound has a 1-substituted purine ring with a hydrogen atom at the 1-position.

Substituents

3,7-dihydro-8-(4-methoxyphenyl)-1,3-dimethyl
The 8-(4-methoxyphenyl) substituent indicates the presence of a methoxy group (-OCH3) attached to a phenyl ring at the 4-position, which is connected to the purine core at the 8-position.

Biological significance

Found in various biological molecules
Purines are essential components of nucleic acids (DNA and RNA) and are involved in the storage and transmission of genetic information.

Physiological functions

Important physiological functions
Purines play a crucial role in various biological processes, including energy metabolism, signal transduction, and regulation of enzyme activity.

Pharmacological properties

May be affected by substituents
The presence of a methyl group and a methoxyphenyl group on the purine core may influence the compound's pharmacological properties, such as its solubility, stability, and interaction with biological targets.

Medicinal applications

Potential for further research and development
Due to its unique structure and potential biological activity, this compound may be of interest for the development of new drugs or therapeutic agents.

Upstream product

• 122-51-0 orthoformic acid triethyl ester 
• 60333-34-8 6-amino-5-(4-methoxy-benzylideneamino)-1,3-dimethyl-1H-pyrimidine-2,4-dione 
• 50996-16-2 5,6-diamino-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione hydrochloride 
• 123-11-5 4-methoxy-benzaldehyde 
• 90994-72-2 6-(4-Methoxy-benzylamino)-1,3-dimethyl-5-nitro-1H-pyrimidine-2,4-dione 
• 42748-13-0 4-methoxy-benzaldehyde (1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-pyrimidin-4-yl)-hydrazone 
• 60333-34-8 6-Amino-5-(4-methoxybenzylideneamino)-1,3-dimethyluracil 
• 166115-69-1 N-(6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl)-4-methoxy-benzamide 
• 5440-00-6 4,5-Diamino-1,3-dimethyluracil 
• 2393-23-9 4-methoxy-benzylamine 
• 1203-25-4 6-chloro-1,3-dimethyl-5-nitrouracil 
• 100-09-4 4-methoxybenzoic acid 

Relevant articles and documents

Exploration of polystyrene-supported 2-isobutoxy-1-isobutoxycarbonyl-1,2- dihydroquinoline (PS-IIDQ) as new coupling agent for the synthesis of 8-substituted xanthine derivatives

Polystyrene-supported 2-isobutoxy-1-isobutoxycarbonyl-1,2-dihydroquinoline (PS-IIDQ), a polymer supported covalent coupling reagent, was successfully employed for the first time in the synthesis of 8-substituted xanthine derivatives. PS-IIDQ was observed

Synthesis, DNA binding and antiviral activity of new uracil, xanthine, and pteridine derivatives

Some new 6-amino-1,3-dimethyl-5-(substituted methylidene)aminouracils were synthesized. Most of them were cyclized with triethyl orthoformate as a one-carbon source to afford 1,3-dimethyl-6-substituted pteridine derivatives. Certain uracils gave xanthine

Synthesis and in vitro bronchospasmolytic activity of 8-aryl, heteroaryl or arylalkyl theophyllines

Twenty-four 8-aryl- or 8-heteroaryl-substituted theophyllines have been synthesized.The substituents are aromatic rings and heterocycles likely to induce an antiallergic effect or a spasmolytic activity.In vitro evaluation of the bronchospasm caused by ac

REACTIONS OF 5,6-DIAMINO-1,3-DIMETYLURACIL WITH HALOGEN DERIVATIVES OF CHALCONES

The reaction of 5,6-diamino-1,3-dimethyluracil with 1,3-diaryl-2,3-dibromopropan-1-ones gave β-(5-amino-6-imino-1,3-dimethyluracil)chalcones, and conditions for their cyclocondensation to pyrimidinodiazepines were found.For substantiation of the reaction mechanism, the reaction of the diamine with other halogen derivatives of chalcones was studied.The IR, UV, and mass spectra of the synthesized compounds and their condensation products are discussed.

Reaction of 6-Arylidenehydrazino-1,3-dimethyluracils with Thionyl Chloride Leading to Purine, Thiazolopyrimidine, Pyrimidothiadiazine, Pyrazolopyrimidine, and Thiadiazolopyrimidine Derivatives

The reaction of 6-arylidenehydrazino-1,3-dimethyluracils with thionyl chloride in benzene afforded purine, thiazolopyrimidine, pyrimidothiadiazine, pyrazolopyrimidine, and thiadiazolopyrimidine derivatives, while

A NEW CONTRACTION OF PTERIDINE 5-OXIDES TO PURINES AND A 7-DEAZAPURINE BY THE 1,3-DIPOLAR CYCLOADDITION REACTION

The 1,3-dipolar cycloaddition reaction of pteridine 5-oxides with dimethyl acetylenedicarboxylate resulted in a new ring contraction of the pyrazine moiety to give purines and a 7-deazapurine.

Pyrimidine Derivatives and Related Compounds. Part 47. A New Synthesis of Xanthines and Pyrrolopyrimidines by Intramolecular Cyclisation of 6-Substituted 5-Nitrouracil Derivatives

6-Arylalkylamino-1,3-dimethyl-5-nitrouracils (2a-f) were prepared by reaction of 6-chloro-1,3-dimethyl-5-nitrouracil (1) with arylalkylamines in the presence of triethylamine.Among them, the 6-arylalkylaminouracils (2a-d), possessing no substituent at the