96734-86-0

Upstream product

• 27143-10-8 ethoxycarbonylformyl chloride p-bromophenylhydrazone 
• 123-54-6 acetylacetone 
• 106-40-1 4-bromo-aniline 
• 27143-10-8 ethyl (Z)-2-chloro-2-(2-(4-bromophenyl)hydrazono)acetate 

Downstream Products

• 132363-08-7 2-(4-Bromo-phenyl)-7-chloro-3,4-dimethyl-2H-pyrazolo[3,4-d]pyridazine 
• 132330-68-8 2-(4-Bromo-phenyl)-3,4-dimethyl-6-(4-nitro-phenyl)-2,6-dihydro-pyrazolo[3,4-d]pyridazin-7-one 
• 132330-65-5 2-(4-bromophenyl)-3,4-dimethyl-6-phenyl-2,6-dihydro-7H-pyrazolo[3,4-d]pyridazin-7-one 
• 132330-62-2 2-(4-Bromo-phenyl)-3,4-dimethyl-2,6-dihydro-pyrazolo[3,4-d]pyridazin-7-one 
• 132330-71-3 4-[2-(4-Bromo-phenyl)-3,4-dimethyl-7-oxo-2,7-dihydro-pyrazolo[3,4-d]pyridazin-6-yl]-benzoic acid 

Relevant academic research and scientific papers

In Situ Generation of Nitrilimines from Aryldiazonium Salts and Diazo Esters: Synthesis of Fully Substituted Pyrazoles under Room Temperature

A novel one-pot synthesis for fully substituted pyrazoles has been well developed via the in situ generation of nitrilimines from aryldiazonium salts and diazo esters and a subsequent cycloaddition with 1,3-dicarbonyl compounds. High yields, mild conditio

1,3-Dipolar Cycloaddition of Four Hydrazonoyl Chlorides to β-Diketones and α,β-Unsaturated Ketones

The 1,3-dipolar cycloaddition of four hydrazonoyl chloride derivatives with the sodium salt of unsymmetrical β-diketones (benzoylacetone) offers a versatile method for the regioselective synthesis of 2H-pyrazoles in a similar fashion to the cycloaddition of the nitrilimides with α,β-unsaturated ketones and esters. The structures of the prepared isomeric pyrazole and pyrazoline derivatives were established by spectroscopic and chemical methods.

The Regioselectivity of the 1,3-Dipolar Cycloaddition of α-Carbonylformonitrile N-arylimides To Benzylideneacetone and β-Diketones

The cycloaddition of the ethoxycarbonylformonitrile N-arylimides 2 to benzylideneacetone afforded two regioisomers, 5-acetyl- and 4-acetyl-dihydropyrazole but the cycloaddition of 2 to benzoylacetone afforded two regioisomers, 4-acetyl- and 4-benzoylpyrazole.Also, some pyrazolopyridazin-7-one and pyrazolopyridazinderivatives were synthesized.