96751-50-7

Upstream product

• 29203-58-5 4-bromo-N-hydroxybenzenecarboximidoyl chloride 
• 614-21-1 2-nitroacetophenone 
• 3156-37-4 (E)-1-bromo-4-(2-nitrovinyl)benzene 
• 873-67-6 benzonitrile oxide 
• 95310-17-1 trans-3-phenyl-4-nitro-5-(p-bromophenyl)-4,5-dihydro-1,2-oxazole 
• 95310-17-1 (4R,5R)-5-(4-Bromo-phenyl)-4-nitro-3-phenyl-4,5-dihydro-isoxazole 

Relevant academic research and scientific papers

Trifluoromethylation of aromatic isoxazoles: Regio- and diastereoselective route to 5-trifluoromethyl-2-isoxazolines

It all adds up: The activation of aromatic isoxazoles with a nitro group at the 4-position has enabled the first regio- and diastereoselective trifluoromethylation at the 5-position of isoxazoles by nucleophilic addition using Me3SiCF3 (see scheme; DMF=N,N′- dimethylformamide). The process was demonstrated with a broad range of 3,5-aromatic, heteroaromatic and aliphatic substrates.

SYNTHESIS AND PROPERTIES OF AZOLES AND THEIR DERIVATIVES. PART XX. STUDIES ON THE THERMOLYSIS OF REGIO AND STEREOISOMERIC DIARYLNITRO-Δ2-ISOXAZOLINES

Thermolysis of stereoisomeric 3,5-diaryl-4-nitro-Δ2-isoxazolines 1, 3, depending on the applied solvent, leads to 3,5-diarylisoxazoles 4 or mixtures of 3,5-diarylisoxazoles 4 and 3,5-diaryl-4-nitroisoxazoles 6.Under similar conditions, 3,4-diar

SYNTHESIS AND PROPERTIES OF 4-HALO-4-NITROISOXAZOLINES

Chloro-, bromo-, and iodo-derivatives of substituted 4-nitroisoxazolines have been synthesized by direct halogenation of the latter, and their chemical properties have been studied, among them their conversion to 4-nitroisoxazole derivatives by eliminatio

SYNTHESIS AND PROPERTIES OF AZOLS AND THEIR DERIVATIVES. PART XII. REGIO- AND STEREOCHEMISTRY IN CYCLOADDITION REACTIONS OF β-NITROSTYRENES WITH BENZONITRILE n-OXIDE

1,3-Dipolar cycloaddition of trans-β-nitrostyrenes 1a-d to benzonitrile N-oxide 2 has been investigated.It was found that regioisomeric 4,5-dihydro-1,2-oxazoles were formed as primary products due to two possible orientations of reactants in the transitio

SYNTHESIS AND PROPERTIES OF AZOLES AND THEIR DERIVATIVES. 10. SYNTHESIS OF 3,5-DIARYL-4-NITROISOXAZOLES

A method was proposed for the synthesis of 3,5-diaryl-4-nitroisoxazoles entailing the bromination of potassium salts of the corresponding 3,5-diaryl-Δ2-isoxazolinyl-4-nitronic acids.The method may be used for the conversions of both the trans and cis isomers of 3,5-disubstituted 4-nitro-Δ2-isoxazolines.