96753-46-7Relevant academic research and scientific papers
Pyridazines. XXIII . A Novel Pyridazine into Pyrazole Ring Transformation
Heinisch, Gottfried,Waglechner, Richard
, p. 1727 - 1731 (2007/10/02)
Treatment of phenyl(4-pyridazinyl)methanols 1a and 1b with p-toluenesulfonic acid at elevated temperatures causes transformation into the C-4 substituted pyrazole derivatives 8a and 8b.Limitations of this novel rearrangement reaction as well as mechanistic considerations are discussed.Furthemore, the preparation of hitherto unknown 4-pyridazinylmethanols 1b, 3, and 7 is described.
