96835-28-8

Upstream product

• 1072-85-1 o-fluorobromobenzene 
• 2459-09-8 4-pyridinecarboxylic acid, methyl ester 
• 41538-36-7 4-(4-fluorobenzoyl)pyridine 
• 460-00-4 1-Bromo-4-fluorobenzene 
• 1120-87-2 4-bromopyridin 
• 345-92-6 4,4'-Difluorobenzophenone 
• 1570-45-2 isonicotinic acid ethylester 

Downstream Products

• 96835-34-6 4-[Bis-(4-fluoro-phenyl)-hydroxy-methyl]-1-methyl-pyridinium; iodide 
• 60284-98-2 1,1-bis(4-fluorophenyl)-1-(4-piperidinyl)methanol 
• 96835-08-4 Bis-(4-fluoro-phenyl)-(1-methyl-1,2,3,6-tetrahydro-pyridin-4-yl)-methanol 

Relevant academic research and scientific papers

NOVEL COMPOUNDS AS CALCIUM CHANNEL BLOCKERS

The present application relates to calcium channel inhibitors containing compounds of formula (I) wherein Ar1, Ar2, L1, L2, n, R1, R4, X and Y are as defined in the specification. The present application also relates to compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.

Arylalkylheterocyclic amines,N-substituted by aryloxyalkyl group in a method for allergy treatment

A method of inhibiting Type 1 allergic responses in a living animal body with substituted heterocyclic amines is disclosed wherein the active agents are expressed generally by the formula which includes certain known and certain known compounds: STR1 wherein P is zero, one or two; m is one to six inclusive; A is selected from hydrogen, hydroxy or cyano; d is zero or one; Q is --CH--, CH2 -- or STR2 n is zero or one and when Q is --CH-- and n is one, a double bond is formed with one of the adjacent carbons but not both at the same time, and when n and d are zero at the same time, a double bond is formed between the α carbon and a carbon of the central heterocyclic amine ring; Ar, D and R are selected from phenyl, substituted phenyl, pyridinyl, thienyl, furanyl or naphthyl and in addition, R may have the values benzyl, substituted benzyl, cycloalkyl or loweralkyl and D may additionally have the values: 2H-1-benzopyran-2-one,4-oxo-4H-1-benzopyran-2-carboxylic acid loweralkyl ester, 2,3-dihydro-4H-1-benzopyran-4-one, 1,4-benzodioxanloweralkyl-2-yl or 1,1'-biphenyl-4-yl and the pharmaceutically acceptable salts thereof.

Substituted N-benzyl-4-(benzhydryl) piperidines

The invention relates to compounds of the formula: STR1 which are useful cardiovascular agents.

Antiimplantation Agents: Part IV - 4-Benzhydrylidenepiperidines and Tetrahydropyran Analogues of F 6066

Several α-(4-pyridyl)enzhydrols (8) have been synthesised by Grignard reaction on 4-aroylpyridines (6) or ethyl isonicotinate (7).The quaternary salts 9 of 8 are reduced catalytically to α-(4-piperidyl)benzhydrols (10) which undergo dehydration to benzhyd

[[Bis(aryl)methylene]-1-piperidinyl]alkyl-pyrimidinones

Novel [[bis(aryl)methylene]-1-piperidinyl]alkyl-pyrimidinones, wherein the pyrimidinone-ring is embraced within a bicyclic system, being useful compounds in the treatment of psychosomatic disorders.