60284-98-2

Basic information

• Product Name: alpha,alpha-bis-(4-Fluorophenyl)piperidine-4-methanol
• Synonyms: alpha,alpha-bis-(4-Fluorophenyl)piperidine-4-methanol;bis(4-fluorophenyl)(piperidin-4-yl)methanol
• CAS NO: 60284-98-2
• Molecular Formula: C₁₈H₁₉F₂NO
• Molecular Weight: 303.3463664
• Mol File: 60284-98-2.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: alpha,alpha-bis-(4-Fluorophenyl)piperidine-4-methanol(CAS DataBase Reference)
• NIST Chemistry Reference: alpha,alpha-bis-(4-Fluorophenyl)piperidine-4-methanol(60284-98-2)
• EPA Substance Registry System: alpha,alpha-bis-(4-Fluorophenyl)piperidine-4-methanol(60284-98-2)

Safety Data

• Hazardous Substances Data: 60284-98-2(Hazardous Substances Data)

Upstream product

• 460-00-4 1-Bromo-4-fluorobenzene 
• 96835-28-8 α,α-bis(4-fluorophenyl)-4-pyridinemethanol 
• 142851-03-4 1-tert-butyl 4-ethyl piperidine-1,4-dicarboxylate 
• 24228-40-8 N-benzyl isonipecotic acid ethyl ester 
• 111627-25-9 α,α-bis-(4-fluorophenyl)-1-(phenylmethyl)-4-piperidinemethanol 

Downstream Products

• 111627-01-1 1-[4-[3-[4-[Bis(4-fluorophenyl)hydroxymethyl]-1-piperidinyl]propoxy]-2-methoxyphenyl]ethanone hydrochloride 
• 117023-93-5 1-<4-<3-<4--1-piperidinyl>-2-hydroxypropoxy>-2-hydroxy-3-propylphenyl>ethanone hydrochloride 
• 60284-71-1 AHR 5333 
• 117023-00-4 Bis-(4-fluoro-phenyl)-{1-[3-(2-phenyl-[1,3]dioxolan-2-yl)-propyl]-piperidin-4-yl}-methanol 
• 111626-03-0 1-[3-(4-chlorophenoxy)propyl]-α,α-bis(4-fluorophenyl)-4-piperidinemethanol 
• 117023-60-6 1-[4-[3-[4-[bis(4-fluorophenyl)hydroxymethyl]-1-piperidinyl]propoxy]phenyl]-1-propanone 
• 111626-71-2 1-[4-[2-[4-[bis(4-fluorophenyl)hydroxymethyl]-1-piperidinyl]ethoxy]-3-methoxyphenyl]ethanone 
• 117023-06-0 Bis-(4-fluoro-phenyl)-[1-(4-phenyl-butyl)-piperidin-4-yl]-methanol 
• 117023-09-3 [1-(3-Benzenesulfonyl-propyl)-piperidin-4-yl]-bis-(4-fluoro-phenyl)-methanol 
• 111626-82-5 α,α-[bis(4-fluorophenyl)]-1-[3-[4-(methylthio)phenoxy]propyl]-4-piperidinemethanol 
• 117023-57-1 α,α-Bis(4-fluorophenyl)-1-[3-(4-methoxyphenoxy)propyl]-4-piperidine-methanol 
• 111626-14-3 α,α-bis(4-fluorophenyl)-1-[3-(2-methoxyphenoxy)propyl]-4-piperidinemethanol 
• 111626-33-6 1-[4-[3-[4-[bis(4-fluorophenyl)hydroxymethyl]-1-piperidinyl]propoxy]-phenyl]ethanone 
• 117023-92-4 4--N-phenyl-1-piperidinepropanamide 

Relevant articles and documents

OXAZINE MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS

The invention provides new heterocyclic compounds having the general formula (Ic) wherein A, L, X, m, n and R20 to R23 are as described herein, compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds.

Benzopyranones, a method for producing them and uses therefor

Novel 2H-1-benzopyran-2-ones (coumarin derivatives) of the general formula (I) are provided: STR1 wherein R1, R2, R3, R4, X and Y are defined as in the specification, and the addition compounds thereof with physiologically compatible acids, intermediates and methods for the preparation thereof. The coumarin compounds possess a neuroprotective and anti-allergic action.

Arylalkylheterocyclic amines,N-substituted by aryloxyalkyl group in a method for allergy treatment

A method of inhibiting Type 1 allergic responses in a living animal body with substituted heterocyclic amines is disclosed wherein the active agents are expressed generally by the formula which includes certain known and certain known compounds: STR1 wherein P is zero, one or two; m is one to six inclusive; A is selected from hydrogen, hydroxy or cyano; d is zero or one; Q is --CH--, CH2 -- or STR2 n is zero or one and when Q is --CH-- and n is one, a double bond is formed with one of the adjacent carbons but not both at the same time, and when n and d are zero at the same time, a double bond is formed between the α carbon and a carbon of the central heterocyclic amine ring; Ar, D and R are selected from phenyl, substituted phenyl, pyridinyl, thienyl, furanyl or naphthyl and in addition, R may have the values benzyl, substituted benzyl, cycloalkyl or loweralkyl and D may additionally have the values: 2H-1-benzopyran-2-one,4-oxo-4H-1-benzopyran-2-carboxylic acid loweralkyl ester, 2,3-dihydro-4H-1-benzopyran-4-one, 1,4-benzodioxanloweralkyl-2-yl or 1,1'-biphenyl-4-yl and the pharmaceutically acceptable salts thereof.