96835-41-5Relevant academic research and scientific papers
Symmetric 4,4′-(piperidin-4-ylidenemethylene)bisphenol derivatives as novel tunable estrogen receptor (ER) modulators
Sato, Manabu,Ohta, Kiminori,Kaise, Asako,Aoto, Sayaka,Endo, Yasuyuki
, p. 1089 - 1094 (2016/02/19)
We designed and synthesized 4,4′-(piperidin-4-ylidenemethylene)bisphenol derivatives as novel tunable estrogen receptor (ER) modulators. The introduction of hydrophobic substituents on the nitrogen atom of the piperidine ring enhanced ERα binding affinity
Antiimplantation Agents: Part IV - 4-Benzhydrylidenepiperidines and Tetrahydropyran Analogues of F 6066
Nagarajan, K.,Talwalker, P. K.,Shah, R. K.,Shenoy, S. J.
, p. 112 - 118 (2007/10/02)
Several α-(4-pyridyl)enzhydrols (8) have been synthesised by Grignard reaction on 4-aroylpyridines (6) or ethyl isonicotinate (7).The quaternary salts 9 of 8 are reduced catalytically to α-(4-piperidyl)benzhydrols (10) which undergo dehydration to benzhyd
