67916-57-8

Upstream product

• 2459-09-8 4-pyridinecarboxylic acid, methyl ester 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 100-48-1 pyridine-4-carbonitrile 
• 90-96-0 bis(p-methoxyphenyl)methanone 
• 1570-45-2 isonicotinic acid ethylester 

Downstream Products

• 96835-35-7 4-[Hydroxy-bis-(4-methoxy-phenyl)-methyl]-1-methyl-pyridinium; iodide 
• 1063745-77-6 4-[bis(4-methoxyphenyl)-4-pyridylmethyl]phenol 
• 1404451-20-2 C₂₀H₁₈NO₂⁽¹⁺⁾ 
• 96835-41-5 4-[(4-hydroxyphenyl)(N-methylpiperidin-4-ylidene)methyl]phenol 
• 96835-43-7 Acetic acid 4-[(4-acetoxy-phenyl)-(1-methyl-piperidin-4-ylidene)-methyl]-phenyl ester 
• 96835-10-8 Bis-(4-methoxy-phenyl)-(1-methyl-1,2,3,6-tetrahydro-pyridin-4-yl)-methanol 
• 96835-38-0 Bis-(4-methoxy-phenyl)-(1-methyl-[4]piperidyl)-methanol 
• 94909-58-7 4-(4,4'-dimethoxy-benzhydrylidene)-1-methyl-piperidine 

Relevant academic research and scientific papers

Selective detection of nerve agent simulants by using triarylmethanol-based chromogenic chemodosimeters

A family of triarylcarbinols 1-11 has been synthesised, and the chromogenic behaviour of the members in the presence of nerve-agent simulants diethylcyanophosphonate (DCNP) and diisopropylfluorophosphate (DFP) in acetonitrile and in buffered mixed water/acetonitrile solutions has been investigated. Hydrophobic polyethylene oxide films of these compounds have been prepared. Some of these triarylcarbinols act as OFF/ON chemodosimeters for the nerve agent simulants. The sensing mechanism includes phosphorylation of the hydroxyl group in the triarylcarbinol derivatives, followed by a dephosphatation reaction induced by the electron-donor groups present in the structure. The existence of additional tert-butyldimethylsilyl ether groups in compounds 2 and 3 permits these reagents to act as double probes by allowing selective signalling of DFP. The reactivity between 1 and 4-6 with DFP and DCNP in acetonitrile or water/acetonitrile solutions under pseudo first-order kinetic conditions was studied to determine rate constants (k) and the half-life times (t1/2) for the corresponding reactions. Films containing compound 2 were used to detect simulants both in solution and in the vapour phase. Finally, a logic device was designed that incorporated compounds 2, 14, and 15 that allowed detection of DFP (a Sarin and Soman simulant) and DCNP (a Tabun simulant), even in the presence of possible interferents such as acids. Triarylmethanol derivatives as visual OFF/ON chromodosimeters of nerve-agent simulants (DCNP and DFP), even in water/acetonitrile (3:1 v/v) solutions, were investigated. The developed compounds were able to act as double probe systems and allowed the selective signalling of DFP. Films of compound 2 were used to detect the simulants in solution and in the vapour phase. Copyright

Nanostructured columnar and cubic liquid-crystalline assemblies consisting of unconventional rigid mesogens based on triphenylmethanes

Liquid-crystalline (LC) molecules of unconventional shapes that form columnar and micellar cubic structures have been synthesized using triarylmethyl moieties as building blocks. The molecules have bowl- and dumbbell-shape. Despite the rigidity and bulkiness of the triarylmethyl moieties, the molecules form columnar and micellar cubic LC phases. The bowl-shaped molecules containing one triarylmethyl moiety show LC phases. The LC temperature ranges of the dumbbell-shaped molecules containing two triarylmethyl moieties connected by rigid rods are wider than those of bowl-shaped molecules containing one triarylmethyl moiety. The UV-vis spectroscopy of the dumbbell-shaped molecules having a terphenyl moiety reveals that the terphenyl moieties aggregate in the mesophase.

Antiimplantation Agents: Part IV - 4-Benzhydrylidenepiperidines and Tetrahydropyran Analogues of F 6066

Several α-(4-pyridyl)enzhydrols (8) have been synthesised by Grignard reaction on 4-aroylpyridines (6) or ethyl isonicotinate (7).The quaternary salts 9 of 8 are reduced catalytically to α-(4-piperidyl)benzhydrols (10) which undergo dehydration to benzhyd