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Upstream product

• 3490-06-0 N-methylhomoveratrylamine 
• 7306-46-9 4-chloromethyl-1,2-dimethoxy-benzene 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 
• 144344-81-0 N-(3,4-dimethoxybenzyl)-N'-formyl-2-(3,4-dimethoxyphenyl)ethanamine 
• 50-00-0 formaldehyd 
• 24997-85-1 N-<2-(3,4-dimethoxybenzyl)(3,4-dimethoxyphenyl)>ethanamine 
• 18034-37-2 N-<2-(3,4-dimethoxybenzyl)ethyl>-3,4-dimethoxybenzaldimine 
• 63375-81-5 2-(2-bromo-4,5-dimethoxyphenylphenyl)ethan-1-amine 
• 82040-74-2 2-bromo-4,5-dimethoxy-β-nitrostyrene 
• 116760-19-1 2-bromo-N-(2-bromo-4,5-dimethoxybenzyl)-4,5-dimethoxy-N-methyl-β-phenethylamine 

Relevant academic research and scientific papers

SYNTHESIS BASED ON &β-PHENYLETHYLAMINES. IV. SYNTHESIS AND ANTIARRHYTHMIC ACTIVITY OF SUBSTITUTED PHENYLALKYLAMINES AND N-BENZYLTETRAHYDROISOQUINOLINES

A number of N-benzyltetrahydroisoquinolines forming analogues of sendaverine have been synthesized.Results on the pharmacological activity of the compounds synthesized are presented.

Ruthenium dioxide in fluoro acid medium. III. Aplication to the synthesis of aporphinic, homoaporphinic and dibenzazocinic alkaloids. Studies towards the preparation of azafluoranthenic skeleton

Intramolecular oxidative couplings of phenylalkyltetrahydroisoquinoline precursors in aporphinic and homoaporphinic alkaloids by using RuO2,2H2O in fluoro acidic media were performed. A comparative study of our reagent with TTFA has been made with different precursors. The procedure was also extended to the synthesis of one dibenzazocinic alkaloid. Then, we attempted to synthetize the azafluoranthenic ring, using phenolic and non phenolic isoquinoline precursors.

A Convenient Synthesis of Apogalanthamine Analogues as α-Adrenergic Blocking Agents using Zerovalent Nickel

The apogalanthamine analogues, 5,6,7,8-tetrahydrodibenzazocine (2) and its N-methyl and N-acetyl derivatives (1 and 3), and the methoxy derivatives (4, 5 and 9) of (1) were obtained in good yields by cyclization of the corresponding halogeno-N-benzyl-β-phenethylamines (10a, 11a-d, 12a,b and 13a-c) using stoichiometric amounts of zerovalent nickel generated in situ and potassium iodide.