96839-24-6Relevant articles and documents
SYNTHESIS BASED ON &β-PHENYLETHYLAMINES. IV. SYNTHESIS AND ANTIARRHYTHMIC ACTIVITY OF SUBSTITUTED PHENYLALKYLAMINES AND N-BENZYLTETRAHYDROISOQUINOLINES
Vinogradova, V. I.,Golodnyuk, T. I.,Tulyaganov, N.,Yunusov, M. S.,Baratov, N. Yu.
, p. 341 - 345 (2007/10/02)
A number of N-benzyltetrahydroisoquinolines forming analogues of sendaverine have been synthesized.Results on the pharmacological activity of the compounds synthesized are presented.
A Convenient Synthesis of Apogalanthamine Analogues as α-Adrenergic Blocking Agents using Zerovalent Nickel
Kihara, Masaru,Itoh, Joji,Iguchi, Seiichiro,Imakura, Yasuhiro,Kobayashi, Shigeru
, p. 157 - 177 (2007/10/02)
The apogalanthamine analogues, 5,6,7,8-tetrahydrodibenzazocine (2) and its N-methyl and N-acetyl derivatives (1 and 3), and the methoxy derivatives (4, 5 and 9) of (1) were obtained in good yields by cyclization of the corresponding halogeno-N-benzyl-β-phenethylamines (10a, 11a-d, 12a,b and 13a-c) using stoichiometric amounts of zerovalent nickel generated in situ and potassium iodide.