96923-93-2Relevant academic research and scientific papers
Discovery of a novel class of aldol-derived 1,2,3-triazoles: Potent and selective inhibitors of human cytochrome P450 19A1 (aromatase)
McNulty, James,Nair, Jerald J.,Vurgun, Nesrin,Difrancesco, Benjamin R.,Brown, Carla E.,Tsoi, Bernice,Crankshaw, Denis J.,Holloway, Alison C.
, p. 718 - 722 (2012)
The discovery of a novel five-component 1,2,3-triazole-containing pharmacophore that exhibits potent and selective inhibition of aromatase (CYP 450 19A1) is described. All compounds are derived from an initial aldol reaction of a phenylacetate derivative
