96953-45-6Relevant academic research and scientific papers
Cu(I)-catalyzed transannulation of N -heteroaryl aldehydes or ketones with alkylamines via C(sp3)-H amination
Li, Mingyang,Xie, Ying,Ye, Yong,Zou, Yong,Jiang, Huanfeng,Zeng, Wei
, p. 6232 - 6235 (2015)
A copper(I)-catalyzed direct transannulation of N-heteroaryl aldehydes or ketones with alkylamines via Csp3-H amination has been achieved using molecular oxygen as a sole oxidant. N-Heteroarenes are employed as the amine source. This transformation provides a rapid and concise access to multifunctional imidazo[1,5-a]pyridines.
Regioselective C-H Phosphorothiolation of (Hetero)arenes Enabled by the Synergy of Electrooxidation and Ultrasonic Irradiation
Meng, Ze-Yin,Feng, Cheng-Tao,Zhang, Ling,Yang, Qing,Chen, De-Xiang,Xu, Kun
supporting information, p. 4214 - 4218 (2021/05/26)
An electrochemically regioselective C-H phosphorothiolation of (hetero)arenes with thiocyanate as the S source under ultrasonic irradiation has been developed. The synergistic cooperation of electrooxidation and ultrasonication markedly accelerated the C-H phosphorothiolation reaction. This mechanistically different method is distinguished by its wide substrate scope and transition-metal-free and external-oxidant-free conditions, thus complementing the existing metal-catalyzed or peroxide-mediated protocols for the green synthesis of S-(hetero)aryl phosphorothioates.
Synthesis of imidazo[1,5-a]pyridines via cyclocondensation of 2-(aminomethyl)pyridines with electrophilically activated nitroalkanes
Aksenov, Alexander V.,Aksenov, Dmitrii A.,Arutiunov, Nikolai A.,Maliuga, Vladimir V.,Rubin, Michael
supporting information, p. 2903 - 2910 (2020/12/23)
Imidazo[1,5-a]pyridines were efficiently prepared via the cyclization of 2-picolylamines with nitroalkanes electrophilically activated in the presence of phosphorous acid in polyphosphoric acid (PPA) medium.
