Cu(I)-catalyzed transannulation of N -heteroaryl aldehydes or ketones with alkylamines via C(sp3)-H amination

Article abstract of DOI:10.1021/ol503165b

A copper(I)-catalyzed direct transannulation of N-heteroaryl aldehydes or ketones with alkylamines via C_sp³-H amination has been achieved using molecular oxygen as a sole oxidant. N-Heteroarenes are employed as the amine source. This transformation provides a rapid and concise access to multifunctional imidazo[1,5-a]pyridines.