96999-05-2

Upstream product

• 134-20-3 2-carbomethoxyaniline 
• 115-80-0 Triethyl orthopropionate 
• 31499-90-8 2,1-benzisoxazol-3(1H)-one 

Downstream Products

• 94209-49-1 2-(2-ethyl-4-oxo-4H-quinazolin-3-yl)-benzoic acid methyl ester 
• 50547-51-8 3-amino-2-ethylquinazoline-4(3H)-one 

Relevant academic research and scientific papers

Synthesis of 3-Amino-4-(3H)-quinazolinones from N-(2-Carbomethoxyphenyl) Imidate Esters

Novel difunctional aromatic synthons consisting of N-(2-carbomethoxyphenyl) imidate esters were synthesized by treatment of methyl anthranilate esters with aliphatic ortho esters.Treatment of the imidates with hydrazine, methylhydrazine, and phenylhydrazine yielded only quinazolinones and not isomeric 1,3,4-benzotriazepin-5-ones.The type of products obtained gave information relevant to elucidation of the mechanism of cyclization and the relative reactivities of the ester and imidate groups.