97-10-9

Basic information

• Product Name: 4-(methylsulphonyl)-2-nitrophenol
• Synonyms: 4-(methylsulphonyl)-2-nitrophenol;4-(Methylsulfonyl)-2-nitrophenol;4-Hydroxy-3-nitrophenyl methyl sulphone, 2-Hydroxy-5-(methylsulphonyl)nitrobenzene
• CAS NO: 97-10-9
• Molecular Formula: C₇H₇NO₅S
• Molecular Weight: 217.19918
• EINECS: 202-560-3
• Mol File: 97-10-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 405.2°Cat760mmHg
• Flash Point: 198.9°C
• Appearance: /
• Density: 1.535g/cm³
• Vapor Pressure: 3.8E-07mmHg at 25°C
• Refractive Index: 1.59
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 4-(methylsulphonyl)-2-nitrophenol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(methylsulphonyl)-2-nitrophenol(97-10-9)
• EPA Substance Registry System: 4-(methylsulphonyl)-2-nitrophenol(97-10-9)

Safety Data

• Hazardous Substances Data: 97-10-9(Hazardous Substances Data)

Usage

General Description

4-(methylsulphonyl)-2-nitrophenol, also known as 4-MSO, is a chemical compound with the molecular formula C7H7NO5S. It is a yellow crystalline solid that is commonly used as a fungicide and insecticide. 4-MSO is known for its antifungal and antibacterial properties, making it an effective ingredient in agricultural and industrial applications. It works by inhibiting the growth of microorganisms and pests, making it a valuable tool in the control of crop diseases and agricultural pests. Additionally, 4-MSO has also been studied for its potential use in pharmaceuticals and medical applications due to its antimicrobial properties. However, it is important to handle 4-MSO with caution as it is toxic to aquatic life and may cause skin and eye irritation in humans.

InChI:InChI=1/C7H7NO5S/c1-14(12,13)5-2-3-7(9)6(4-5)8(10)11/h2-4,9H,1H3

Upstream product

• 14763-60-1 4-methanesulfonyl-phenol 
• 1073-72-9 4-hydroxythioanisole 
• 637-89-8 4-sulfanylphenol 
• 20945-69-1 4-methanesulfonyl-1-methoxy-2-nitro-benzene 
• 97-07-4 1-chloro-4-methanesulfonyl-2-nitrobenzene 
• 21731-56-6 1-Amino-4-methylsulphonyl-2-nitrobenzene 
• 100621-00-9 bis-(4-methanesulfonyl-2-nitro-phenyl)-ether 
• 453-72-5 1-fluoro-4-methanesulfonyl-2-nitrobenzene 

Downstream Products

• 1820889-23-3 2,2,4-trimethyl-8-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)-6-(methylsulfonyl)-2H-benzo[b][1,4]oxazin-3(4H)-one 
• 32579-33-2 4-(methylsulfonyl)-2-nitro-1-(prop-2-yn-1-yloxy)benzene 
• 20951-27-3 2-Iodo-4-methanesulfonyl-6-nitro-phenol 
• 20951-41-1 2-bromo-4-(methylsulfonyl)-6-nitrophenol 
• 100621-00-9 bis-(4-methanesulfonyl-2-nitro-phenyl)-ether 

Relevant articles and documents

CRYSTALLINE SOLID FORMS OF A BET INHIBITOR

The present application relates to crystalline solid forms of an inhibitor of BET proteins such as BRD2, BRD3, BRD4, and BRD-t, including methods of preparation thereof, and intermediates in the preparation thereof, where the compound is useful in the treatment of diseases such as cancer.

Continuous reduction process

A process for the reduction of aromatic nitro compounds to amino compounds in the liquid phase using iron as reducing agent, which comprises carrying out the reduction continuously such that the reducing iron, based on the amount of nitro compound present in the reactor, is present in an amount substantially in excess of the stoichiometric amount, and effecting the continuous removal of the reaction products such that the substantial excess of reducing iron is also constantly present in the reactor during the reduction.