97-87-0

Usage

Uses

Used in Flavor Industry:
Butyl isobutyrate is used as a flavoring agent for its fruity, sweet taste and aroma, which is reminiscent of pineapple, apple, and banana. It is commonly used in food and beverage products to enhance their flavor and aroma.
Used in Fragrance Industry:
Butyl isobutyrate is used as a fragrance ingredient due to its strong, fresh, fruity odor. It is often used in perfumes, colognes, and other scented products to provide a pleasant and appealing scent.
Used in Essential Oils:
Butyl isobutyrate is found in various essential oils, such as Roman chamomile essential oil, where it contributes to the overall aroma and therapeutic properties of the oil. It is used in aromatherapy for its calming and soothing effects.
Used in Cosmetics and Personal Care Products:
Butyl isobutyrate is used in cosmetics and personal care products, such as lotions, creams, and shampoos, to provide a pleasant scent and enhance the overall sensory experience of using these products.

Preparation

Prepared from the corresponding acid and n-butyl alcohol by esterification in the presence of concentrated H2SO4 with or without solvent (boiling benzene).

InChI:InChI=1/C8H16O2/c1-4-5-6-8(2,3)7(9)10/h4-6H2,1-3H3,(H,9,10)/p-1

Upstream product

• 79-31-2 isobutyric Acid 
• 71-36-3 butan-1-ol 
• 70737-85-8 2-butoxy-2-isopropyl-benzo[1,3]oxathiole 
• 4858-67-7 2-isopropylidene-5,5-dimethyl-[1,3]dioxane-4,6-dione 
• 13112-62-4 iso-butyraldehyde di-n-butyl acetal 
• 24406-16-4 lithium di-n-butylcuprate 
• 81357-56-4 Thioisobutyric acid S-pyridin-2-yl ester 
• 20266-11-9 1-(1-Isobutoxy-2-methyl-propoxy)-butane 
• 123-72-8 butyraldehyde 
• 78-84-2 isobutyraldehyde 
• 109-65-9 1-bromo-butane 
• 129-00-0 pyrene 
• 97-88-1 2-methyl-butyl acrylate 
• 109-69-3 n-Butyl chloride 

Downstream Products

• 778-28-9 butyl para-toluenesulfonate 
• 135-98-8 sec-Butylbenzene 
• 1258239-44-9 3-(2-chloro-phenyl)-2-methyl-propionic acid butyl ester 
• 94041-88-0 methyl (E)-2,2-dimethyl-4-phenyl-3-buten-1-oate 
• 60277-69-2 butyl 2-bromo-2-methylpropanoate 
• 96240-10-7 4-amino-3-isopropyl-1H-1,2,4-triazol-5-(4H)-one 

Relevant academic research and scientific papers

Zr-MOF-808 as Catalyst for Amide Esterification

In this work, zirconium-based metal–organic framework Zr-MOF-808-P has been found to be an efficient and versatile catalyst for amide esterification. Comparing with previously reported homogeneous and heterogeneous catalysts, Zr-MOF-808-P can promote the reaction for a wide range of primary, secondary and tertiary amides with n-butanol as nucleophilic agent. Different alcohols have been employed in amide esterification with quantitative yields. Moreover, the catalyst acts as a heterogeneous catalyst and could be reused for at least five consecutive cycles. The amide esterification mechanism has been studied on the Zr-MOF-808 at molecular level by in situ FTIR spectroscopic technique and kinetic study.

PH-Responsive Pickering emulsion stabilized by polymer-coated silica nanoaggregates and applied to recyclable interfacial catalysis

We first synthesized a diblock copolymer poly[tert-butyl methacrylate]-b-poly[3-(trimethoxysilyl)propyl methacrylate] (PtBMA-b-PTMSPMA) through reversible addition-fragmentation chain transfer (RAFT) living radical polymerization and grafted it onto fumed silica by converting the PTMSPMA segment to silanol and the PtBMA segment to polymethylacrylic acid (PMAA) in the presence of trifluoroacetic acid in order to obtain PMAA brush-coated silica nanoaggregates P-Si. TEM, DLS, FTIR, and TGA results confirmed the successful modification of the starting materials. The nanoaggregates flocculated and stabilized a toluene-in-water Pickering emulsion at low pH, while the nanoaggregates were well dispersed in water and broke the emulsion under both neutral and basic conditions. Alternatively, the addition of acid/base induced emulsification/demulsification cycles that were sustained for several cycles. Moreover, when the P-Si was mixed with Rh-loaded silica, Rh-Si, the mixture had the same pH-responsive Pickering emulsion behavior as the single P-Si. This Pickering emulsion system can be used in the biphasic interfacial catalytic hydrogenation of olefins and had excellent yields under a hydrogen atmosphere. The yield of Pickering emulsion catalysis rapidly reached more than 99% in 3 h, while that of the demulsified mixture failed to reach 20% in 4 h, which verified the promotion of catalysis by the Pickering emulsion. Base-induced demulsification can be used to separate the products and recycle the catalyst. This pH-responsive Pickering emulsion catalytic system was capable of several cycles of reuse, and there was no significant decrease in catalytic efficiency even after eight cycles. This journal is

A pH-switched Pickering emulsion catalytic system: High reaction efficiency and facile catalyst recycling

A smart Pickering emulsion catalytic system is constructed, which not only exhibits fivefold reaction rate enhancement effects in comparison to the conventional biphasic system but also can be facilely demulsified by tuning pH, allowing for in situ recycling nanocatalysts.

Facile Protocol for Water-Tolerant "Frustrated Lewis Pair"-Catalyzed Hydrogenation

Despite rapid advances in the field of metal-free, "frustrated Lewis pair" (FLP)-catalyzed hydrogenation, the need for strictly anhydrous reaction conditions has hampered wide-scale uptake of this methodology. Herein, we report that, despite the generally perceived moisture sensitivity of FLPs, 1,4-dioxane solutions of B(C6F5)3 actually show appreciable moisture tolerance and can catalyze hydrogenation of a range of weakly basic substrates without the need for rigorously inert conditions. In particular, reactions can be performed directly in commercially available nonanhydrous solvents without subsequent drying or use of internal desiccants.

Tuning the wettability of mesoporous silica for enhancing the catalysis efficiency of aqueous reactions

A series of mesoporous silica-based catalysts with finely-tuned surface wettability have been synthesized, of which the catalysis efficiency towards aqueous hydrogenations is highly dependent on their surface wettability and can be five times higher than that of the commercial Pd/C catalyst. This journal is the Partner Organisations 2014.

Nematicidal activity of natural ester compounds and their analogues against pine wood nematode, bursaphelenchus xylophilus

In this study, we evaluated the nematicidal activity of natural ester compounds against the pine wood nematode, Bursaphelenchus xylophilus, to identify candidates for the development of novel, safe nematicides. We also tested the nematicidal activity of synthesized analogues of these ester compounds to determine the structure-activity relationship. Among 28 ester compounds tested, isobutyl 2-methylbutanoate, 3-methylbutyl 2-methylbutanoate, 3-methylbutyl tiglate, 3-methyl-2-butenyl 2- methylbutanoate, and pentyl 2-methylbutanoate showed strong nematicidal activity against the pine wood nematode at a 1 mg/ mL concentration. The other ester compounds showed weak nematicidal activity. The LC50 values of 3-methylbutyl tiglate, isobutyl 2-methylbutanoate, 3-methylbutyl 2-methylbutanoate, 3-methyl-2-butenyl 2-methylbutanoate, and pentyl 2- methylbutanoate were 0.0218, 0.0284, 0.0326, 0.0402, and 0.0480 mg/mL, respectively. The ester compounds described herein merit further study as potential nematicides for pine wood nematode control.

Fluorous 4-N,N-dimethylaminopyridium iodide: Recyclable organocatalysts by precipitation for acylation reaction at room temperature

A novel fluorous DMAP quaternary ammonium iodide salt organocatalyst was prepared. This fluorous organocatalyst was successfully employed to the acylation reaction at room temperature without the use of a stoichiometric amount of external base. It could be recovered 3 times from the reaction mixture by simple precipitation with excellent purity for direct reuse.

Esterification of carboxylate-based ionic liquids with alkyl halides

A facile reaction of 1-ethyl-3-methylimidazolium acetate ([EMIm]Ac) with dichloromethane at room temperature was observed with esters among the products. This esterification can be exploited for mild solvent-free esterification with a range of other carboxylate-based ionic liquids and alkyl halides. The Royal Society of Chemistry.

Enhanced Pd-catalyzed hydrogenation of olefins within polymeric microreactors under organic/aqueous biphasic conditions

A microreactor of a water-soluble hollow polymeric microsphere with Pd nanoparticles immobilized in the wall was proposed for the hydrogenation of olefins under organic and aqueous biphasic conditions. It was found that the microreactor was stable and was used in practical application for continuous hydrogenation of olefins on a technical scale without deactivation in activity. It was composed of three parts, such as the outer corona of polyacrylamide (PAM), the cross-linked and hydrophobic wall of poly[styrene-co-2-(acetoacetoxy) -ethylmethacrylate] (PS-co-PAEMA), and 3.9 mm Pd nanoparticles. Hollow microspheres were constructed using several procedures of seed polymerization along with removal of the seed for the synthesis of the microreactor. It was observed that the microreactor dispersed easily in aqueous phase due to the presence of the hydrophilic PAM corona. The hydrogenation of CA with H 2 was also evaluated to investigate hydrogenation of olefins within the microreactor.

DEGRADATION OF POLYCYCLIC AROMATIC HYDROCARBONS TO RENDER THEM AVAILABLE FOR BIODEGRADATION

A method for the degradation of polycyclic aromatic compounds is disclosed that involves dissolving ozone in a bipolar solvent comprising a non-polar solvent in which is of sufficiently non-polar character to solubilized the polycyclic aromatic compounds, and a polar-water-compatible solvent which is fully miscible with the non-polar solvent to form a single phase with the non-polar solvent. The bipolar solvent with dissolved ozone is contacted with the polycyclic aromatic compounds to solubilize the polycyclic aromatic compounds and react the dissolved polycyclic aromatic compounds with the ozone to degrade the dissolved polycyclic aromatic compounds to oxygenated intermediates. The bipolar solvent is then mixed with sufficient water to form separate non-polar and polar phases, the non-polar phase comprising the non-polar solvent and the polar phase comprising the non-polar solvent and the oxygenated intermediates. The polar phase is then diluted and incubated with bacteria to biodegrade the oxygenated intermediates.