97204-92-7

Upstream product

• 933-00-6 p-methylbenzenesulfenyl chloride 
• 3279-26-3 methyl dichlorophosphite 

Downstream Products

• 134218-84-1 2',3'-O,O-(methoxymethylene)uridine 5'- 
• 134241-18-2 2',3'-O,O-(methoxymethylene)uridine 5'- 
• 134219-00-4 Thiophosphoric acid O-(2-cyano-ethyl) ester S-p-tolyl ester O'-(2,2,2-triphenyl-ethyl) ester 
• 134218-98-7 Thiophosphoric acid O-(2-cyano-ethyl) ester O'-(2-naphthalen-1-yl-ethyl) ester S-p-tolyl ester 
• 134218-99-8 Thiophosphoric acid O-[2-(4-bromo-phenyl)-ethyl] ester O'-(2-cyano-ethyl) ester S-p-tolyl ester 
• 134219-02-6 Thiophosphoric acid O-(4-tert-butyl-phenyl) ester O'-(2-cyano-ethyl) ester S-p-tolyl ester 
• 134219-03-7 Thiophosphoric acid O-(2-cyano-ethyl) ester O'-(4-isopropyl-phenyl) ester S-p-tolyl ester 
• 134219-01-5 Thiophosphoric acid O-(2-cyano-ethyl) ester O'-(4-iodo-phenyl) ester S-p-tolyl ester 
• 134219-04-8 Thiophosphoric acid O-(2-naphthalen-1-yl-ethyl) ester S-p-tolyl ester 
• 134219-05-9 Thiophosphoric acid O-[2-(4-bromo-phenyl)-ethyl] ester S-p-tolyl ester 
• 134219-08-2 Thiophosphoric acid O-(4-tert-butyl-phenyl) ester S-p-tolyl ester 
• 134219-09-3 Thiophosphoric acid O-(4-isopropyl-phenyl) ester S-p-tolyl ester 
• 134219-07-1 Thiophosphoric acid O-(4-iodo-phenyl) ester S-p-tolyl ester 
• 97204-93-8 S-4-methylphenyl-O,O-bis(1-benzotriazolyl)phosphorothioate 

Relevant academic research and scientific papers

Synthesis of potential UDP-glucuronosyltransferase inhibitors containing a diphosphate function

The synthesis of potential inhibitors of UDP-glucuronosyltransferase, in which the β-phosphate moiety of uridine 5'-diphosphate is linked to phenolic or alcoholic hydroxyl groups, is described.Key intermediates in the formation of the diphosphate function are S-(4-methylphenyl) 2-cyanoethyl phosphorothioate triesters which, after conversion into the corresponding S-(4-methylphenyl) phosphorothioate diesters, react with phosphate monoesters, in the presence of iodine, to give the target molecules.

S-4-METHYLPHENYL-O,O-BIS(1-BENZOTRIAZOLYL)PHOSPHOROTHIOATE: A VERSATILE PHOSPHORYLATING AGENT

The phosphorylating agent obtained by treatment of S-4-methylphenyl phosphorodichloridothioate with 1-hydroxybenzotriazole can not only be applied for the introduction of polyphosphate functions at the terminal ends of nucleic acids, but also for the formation of 3'-5'-phosphotriester linkages.