97329-87-8

Upstream product

• 97372-48-0 (S)-3-(4-Methyl-3-nitro-phenyl)-butyric acid 
• 865-34-9 lithium methanolate 
• 97372-49-1 (S)-3-(3-Methoxy-4-methyl-phenyl)-butyric acid 
• 74-88-4 methyl iodide 
• 69657-27-8 (S)-4-(4-methylphenyl)pentan-2-one 
• 1201-85-0 (S)-3-(4-methylphenyl)butanoic acid 
• 532-65-0 (+)-(S)-ar-turmerone 

Downstream Products

• 97372-50-4 Methyl (S)-(+)-5-(3'-methoxy-4'-methylphenyl)hexanoate 
• 88948-12-3 (S)-5-(3-Methoxy-4-methyl-phenyl)-hexanoic acid 
• 97329-89-0 (S)-3-(3'-Methoxy-4'-methylphenyl)-butanal 
• 97329-88-9 (3S)-3-(3-Methoxy-4-methylphenyl)butan-2-ol 

Relevant academic research and scientific papers

Use of 1,1'-binaphthalene-8,8'-diol as a chiral auxiliary for asymmetric Michael addition. Application to the syntheses of turmeronol A and B

Highly diastereoselective Michael addition of lithium diorganocuprates to the half-ester of 1,1'-binaphthalene-8,8'-diol gave β-substituted esters with high enantiomeric excess after methanolysis. The optically active phenolic sesquiterpenes turmeronol A (1) and B (2) have been synthesized using this reaction as a key step.

Absolute Configuration of Naturally Occuring (-)-Xanthorrhizol

The R-configuration (2) of (-)-xanthorrhizol, a phenolic sesquiterpene occuring in the rhizomes of Curcuma xanthorrhiza has been assigned by synthesis of (S)-(+)-xanthorrhizol (13) from (+)-ar-turmerone (3) of known configuration (S).