97475-41-7

Upstream product

• 89545-46-0 Boc-Val-Orn(Z)-Leu-Pro-OBzl 
• 13734-41-3 t-Boc-L-valine 
• 13139-15-6 N-tert-butoxycarbonyl-L-leucine 
• 16652-71-4 benzyl (2S)-2-pyrrolidinecarboxylate hydrochloride 
• 83610-64-4 leucylproline benzyl ester 
• 83610-44-0 benzyl (2S)-1-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-4-methylpentanoyl]pyrrolidine-2-carboxylate 
• 97475-35-9 H-Orn(Z)-Leu-Pro-OBzl 
• 89545-44-8 Boc-Orn(Z)-Leu-Pro-OBzl 
• 2480-93-5 Boc-Orn(Z)-OH 
• 41324-66-7 H-Pro-OBzl 

Downstream Products

• 95716-15-7 (S)-1-[(S)-2-((S)-5-Benzyloxycarbonylamino-2-{(S)-2-[(R)-2-((R)-2-tert-butoxycarbonylamino-3-phenyl-propionylamino)-3-phenyl-propionylamino]-3-methyl-butyrylamino}-pentanoylamino)-4-methyl-pentanoyl]-pyrrolidine-2-carboxylic acid 
• 95716-14-6 {(S)-4-{(S)-2-[(R)-2-((R)-2-tert-Butoxycarbonylamino-3-phenyl-propionylamino)-3-phenyl-propionylamino]-3-methyl-butyrylamino}-4-[(S)-1-((S)-2-hydrazinocarbonyl-pyrrolidine-1-carbonyl)-3-methyl-butylcarbamoyl]-butyl}-carbamic acid benzyl ester 
• 97475-42-8 Boc-D-Phe-Val-Orn(Z)-Leu-Pro-OSu 
• 97475-31-5 Boc-D-Phe-Val-Orn(Z)-Leu-Pro-OH 
• 97475-43-9 H-D-Phe-Val-Orn(Z)-Leu-Pro-OH 
• 95716-13-5 (S)-1-[(S)-2-((S)-5-Benzyloxycarbonylamino-2-{(S)-2-[(R)-2-((R)-2-tert-butoxycarbonylamino-3-phenyl-propionylamino)-3-phenyl-propionylamino]-3-methyl-butyrylamino}-pentanoylamino)-4-methyl-pentanoyl]-pyrrolidine-2-carboxylic acid benzyl ester 
• 97475-30-4 Boc-D-Phe-Val-Orn(Z)-Leu-Pro-OBzl 

Relevant academic research and scientific papers

Synthesis and properties of gramicidin S analogs containing Pro-D-Phe sequence in place of D-Phe-Pro sequence in the β-turn part of the antibiotic

Two analogs of gramicidin S, [L-Pro4, D-Phe5]-gramicidin S and [L-Pro(4,4'), D-Phe(5,5')]-gramicidin S, were synthesized in order to investigate the relationships among positions of Pro residues, antibiotic activity and CD spectra. [

Studies on peptide antibiotic 'gratisin'

According to a primary structure proposed for an antibiotic peptide, gratisin, four peptides containing respectively partial sequences, L-Phe-L-Pro-L-Tyr, D-Phe-L-Pro-L-Tyr, L-Phe-L-Pro-D-Tyr, and D-Phe-L-Pro-D-Tyr, were synthesized by a liquid phase meth